{"id":13847,"date":"2023-01-10T08:19:07","date_gmt":"2023-01-10T06:19:07","guid":{"rendered":"https:\/\/h3africa.org\/?page_id=13847"},"modified":"2023-01-10T08:29:41","modified_gmt":"2023-01-10T06:29:41","slug":"adekunle-fakunle-2","status":"publish","type":"page","link":"https:\/\/h3africa.org\/index.php\/adekunle-fakunle-2\/","title":{"rendered":"Adekunle Fakunle"},"content":{"rendered":"<p>[vc_row][vc_column][vc_single_image image=&#8221;13473&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_rounded&#8221; css=&#8221;.vc_custom_1673331627491{margin-top: 36px !important;}&#8221;][vc_column_text]<\/p>\n<h3 style=\"text-align: center;\">Adekunle Fakunle<\/h3>\n<h4 style=\"text-align: center;\">H3Africa PI: Mayowa Owolabi<\/h4>\n<hr \/>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Institution:<\/strong> University of Ibadan<\/p>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Project Affiliation:<\/strong> SIREN<\/p>\n<p style=\"font-size: 17px; color: #000000; font-weight: bold;\">Abstract<\/p>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Background:<\/strong> Stroke is a leading cause of morbidity and mortality worldwide, but little is known about the significance of indirect exposure to tobacco smoke(secondhand smoke exposure \u2013SHSE and non-cigarette tobacco use \u2013NCTU) in stroke epidemiology among indigenous Africans. This study aimed to evaluate the association of SHSE and NCTU with first-ever stroke among indigenous Africans.<\/p>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Methods:<\/strong> A total of 7,617 respondents who had never smoked were identified in the Stroke Investigation Research and Educational Network (SIREN) study. A stroke case was defined based on clinical presentation and confirmed with a cranial CT or MRI. At the same time, the main exposure variables, SHSE and NCTU were self-reported using validated instruments. Multivariable-adjusted logistic regression was applied to estimate the adjusted odds ratio (aOR) and 95% confidence interval (CI) for the independent associations of SHSE and NCTU with stroke at a two-sided p&lt;0.05.<\/p>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Results:<\/strong>Mean age of respondents was 59.23 \u00b1 12.20 years with a male proponde race(65.9%). Overall, 19.5% and 0.5% of this sample reported SHSE and NCTU respectively. SHSE was associated with odds of stroke; aOR: 1.25 (95% CI: 1.04, 1.50); P= 0.017,whereas NCTU was associated with a2-fold risk of stroke (aOR: 2.08; 95% CI: 1.02,4.23).Further stratification by stroke types revealed similar trends independent of stroke subtype.<\/p>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Conclusion:<\/strong> Indirect exposure to tobacco smoke was associated with an increased risk of stroke among indigenous Africans. Therefore, public health interventions targeted at impulsive or<br \/>\ninvoluntary tobacco exposure might be promising in reducing the already high burden of stroke among Africans.<\/p>\n<p style=\"font-size: 17px; color: #000000;\"><strong>Keywords:<\/strong> Stroke; Secondhand smoke; Non-cigarette tobacco; Indigenous Africans; SIREN<\/p>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<h3>Other Fellows<\/h3>\n<hr\/>\n<p>[\/vc_column_text][vc_basic_grid post_type=&#8221;page&#8221; max_items=&#8221;-1&#8243; element_width=&#8221;3&#8243; item=&#8221;5653&#8243; grid_id=&#8221;vc_gid:1673332148835-60518b60-563f-4&#8243; taxonomies=&#8221;201&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_single_image image=&#8221;13473&#8243; img_size=&#8221;medium&#8221; alignment=&#8221;center&#8221; style=&#8221;vc_box_rounded&#8221; css=&#8221;.vc_custom_1673331627491{margin-top: 36px !important;}&#8221;][vc_column_text] Adekunle Fakunle<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":2,"featured_media":13473,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":""},"categories":[],"tags":[201],"class_list":["post-13847","page","type-page","status-publish","has-post-thumbnail","hentry","tag-20th_fellows"],"_links":{"self":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/13847","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/comments?post=13847"}],"version-history":[{"count":2,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/13847\/revisions"}],"predecessor-version":[{"id":13849,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/13847\/revisions\/13849"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/media\/13473"}],"wp:attachment":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/media?parent=13847"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/categories?post=13847"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/tags?post=13847"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}