{"id":6155,"date":"2019-03-25T10:13:14","date_gmt":"2019-03-25T10:13:14","guid":{"rendered":"https:\/\/h3africa.org\/?page_id=6155"},"modified":"2022-02-28T15:47:36","modified_gmt":"2022-02-28T13:47:36","slug":"projects-2-2","status":"publish","type":"page","link":"https:\/\/h3africa.org\/index.php\/consortium\/projects-2-2\/","title":{"rendered":"Projects"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text css_animation=”slideInRight” css=”.vc_custom_1644988965239{margin-top: 36px !important;}”]H3Africa projects have been funded between 2011 – 2021 by the National Institutes of Health, Wellcome Trust, African Academy of Sciences, and the Science for Africa Foundation. Members from all project groups participate in the Working Group and Steering Committee activities.<\/p>\n

H3Africa projects investigate the genomics of non-communicable and communicable diseases in African contexts and the Ethical, Legal, and Social Implications (ELSI) of this research. Additionally, there are projects that help develop capacity: biorepositories, the bioinformatics network, a coordinating center, and the bioinformatics training programs.[\/vc_column_text][vc_single_image image=”8930″ img_size=”large” alignment=”center” onclick=”link_image”][vc_btn title=”Download H3Africa Project Map” style=”flat” shape=”square” color=”juicy-pink” align=”center” link=”url:%2Fwp-content%2Fuploads%2F2020%2F09%2Fproject_5.png||target:%20_blank|”][vc_tta_accordion style=”outline” color=”juicy-pink” active_section=”1″ no_fill=”true”][vc_tta_section title=”Biorepositories” tab_id=”1558348983404-a80c182b-bcd9″][vc_column_text]<\/p>\n\n\n\n\n\n\n\n
Project Description<\/th>\nProject Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
H3Africa Regional Biorepositories <\/td>\nEstablishment of an H3Africa Biorepository at Clinical Laboratory Services<\/a><\/td>\nDr. Elizabeth Mayne, Prof. Ute Jentsch<\/td>\nSouth Africa<\/td>\n<\/tr>\n
H3Africa Regional Biorepositories <\/td>\nIntegrated Biorepository of H3Africa Uganda \u2013 IBRH3AU<\/a><\/td>\nProf. Moses Joloba<\/td>\nUganda<\/td>\n<\/tr>\n
H3Africa Regional Biorepositories <\/td>\nIHVN H3 African Biorespository (I-HAB) Initiative<\/a><\/td>\nDr. Alash’le G Abimiku<\/td>\nNigeria<\/td>\n<\/tr>\n
Pilot Biorepository<\/td>\nDevelopment of H3 Africa Biorepositories to Facilitate Studies on Biodiversity, Disease & Pharmacogenomics of African Populations<\/a><\/td>\nDr. Akin Abayomi<\/td>\nSouth Africa<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][vc_btn title=”H3Africa Regional Biorepositories” style=”outline” shape=”round” color=”juicy-pink” i_align=”right” i_icon_fontawesome=”fa fa-download” add_icon=”true” link=”url:https%3A%2F%2Fdrive.google.com%2Ffile%2Fd%2F1k6bjeCuxLesoo80_xJROknPXfHzZUer8%2Fview%3Fusp%3Dsharing||target:%20_blank|”][\/vc_tta_section][vc_tta_section title=”H3Africa Administrative Coordinating Centre” tab_id=”1558353581178-b81f007e-476b”][vc_column_text]<\/p>\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
H3Africa Adminisrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in Africa<\/a><\/td>\nDr. Michelle Skelton<\/td>\nSouth Africa<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Bioinformatics Network” tab_id=”1558353349125-8b54c433-51fb”][vc_column_text]<\/p>\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
H3ABioNet: A Sustainable African Bioinformatics Network for H3Africa<\/a><\/td>\nProf. Nicola Mulder<\/td>\nSouth Africa<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Bioinformatics Training Programs” tab_id=”1558353579025-3067d7fc-8034″][vc_column_text]<\/p>\n\n\n\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
Eastern Africa Network for Bioinformatics Training (EANBIT)<\/a><\/td>\nDaniel Masiga<\/td>\nKenya<\/td>\n<\/tr>\n
Nurturing Genomics and Bioinformatics Research Capacity in Africa (BRECA)<\/a><\/td>\nDr. David Kateete, Dr. Daudi JJingo, Dr. Irving Jordan, Dr. Graeme Mardon<\/td>\nUganda<\/td>\n<\/tr>\n
West African Center of Excellence for Global Health Bioinformatics Research Training<\/a><\/td>\nDr. Seydou Doumbia, Dr. Jian Li, Dr. Jeffrey Shaffer<\/td>\nMali<\/td>\n<\/tr>\n
West African Sustainable Leadership and Innovation Training in Bioinformatics Research (WASLITBRe)<\/a><\/td>\nDr. Ezekiel Adebiyi, Dr. Peter Amoako-Yirenky, Dr. Seydou Doumbia<\/td>\nNigeria<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Collaborative Research Centers” tab_id=”1553507718507-14bc80d0-b081″][vc_column_text]<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
AWI-Gen: Genomic and Environmental Risk Factors for Cardiometabolic Disease in Africans<\/a><\/td>\nMichele Ramsay<\/td>\nSouth Africa, Ghana, Burkina Faso, Kenya<\/td>\n<\/tr>\n
Eyes of Africa: The Genetics of Blindness<\/a><\/td>\nAdeyinka Ashaye<\/td>\nNigeria, Ghana, South Africa, Malawi<\/td>\n<\/tr>\n
Genomic Characterization and Surveillance of Microbial Threats in West Africa<\/a><\/td>\nChristian Happi<\/td>\nNigeria, Senegal, Sierra Leone<\/td>\n<\/tr>\n
Sickle Cell Disease Genomics Network of Africa (SickleGenAfrica)<\/a><\/td>\nSolomon Ofori-Acquah, Gordon Awandare, Julie Makani<\/td>\nGhana, Nigeria, Tanzania<\/td>\n<\/tr>\n
Center for Research on the Respiratory Microbiota of African Children (ReMAC)<\/a><\/td>\nMark Nicol<\/td>\nSouth Africa, The Gambia, Malawi<\/td>\n<\/tr>\n
Systematic Investigation of Blacks with Stroke – Genomics (SIBS-Genomics)<\/a><\/td>\nMayowa Owolabi, Bruce Ovbiagele<\/td>\nNigeria, Ghana<\/td>\n<\/tr>\n
Collaborative African Genomics Network (CAfGEN)<\/a><\/td>\nMogomotsi Matshaba, Gabriel Anabwani, Moses Joloba, Adeodata Kekitiinwa, Graeme Mardon, Sununguko Wata Mpoloka, Oathokwa Nkomazana<\/td>\nBotswana, Eswatini, Uganda<\/td>\n<\/tr>\n
H3Africa Kidney Disease Research Network<\/a><\/td>\nDwomoa Adu, Akinlolu Ojo, Salako Babatunde<\/td>\nGhana, Nigeria, Cameroon<\/td>\n<\/tr>\n
African Collaborative Center for Microbiome and Genomics Research (ACCME)<\/a><\/td>\nClement Adebamowo<\/td>\nNigeria, Zambia<\/td>\n<\/tr>\n
Burden, spectrum and etiology of type 2 diabetes in sub-Saharan Africa<\/a><\/td>\nProf. Ayesha Motala<\/td>\nSouth Africa<\/td>\n<\/tr>\n
TrypanoGEN: An integrated approach to the identification of genetic determinants of susceptibility to trypanosomiasis<\/a><\/p>\n

and<\/p>\n

TrypanoGEN +: The Genetic Determinants of Two Neglected Tropical Diseases<\/a><\/td>\n

Enock Matovu<\/td>\nUganda, Burkina Faso, Democratic Republic of Congo, Zambia, Malawi, Cameroon, Ivory Coast, Guinea<\/td>\n<\/tr>\n
The RHDGen Network: Genetics of rheumatic heart disease and molecular epidemiology of Streptococcus pyogenes pharyngitis<\/a><\/td>\nMark Engel and Bongani Mayosi<\/td>\nSouth Africa<\/td>\n<\/tr>\n
TBGENAfrica: TB Genetics Network in Africa <\/a><\/td>\nDr. Abraham Aseffa<\/td>\nEthiopia<\/td>\n<\/tr>\n
Genetic interactions between human populations and malaria parasites in different environmental settings across Africa<\/a><\/td>\nDr. Alfred Amambua Ngwa<\/td>\nThe Gambia<\/td>\n<\/tr>\n
HI-GENES Africa: Hearing Impairment Genetics Studies in Africa <\/a><\/td>\nProf. Ambroise Wonkam<\/td>\nSouth Africa, Mali, Cameroon<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Research Projects” tab_id=”1553507718535-6cb5d571-da84″][vc_column_text]<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
The Genomics of Schizophrenia in the South African Xhosa People<\/a><\/td>\nDr. Dan Stein, Prof. Raj S. Ramesar<\/td>\nSouth Africa<\/td>\n<\/tr>\n
Transgenerational Effects of Maternal Stressors: Investigating the Role of Infant Gene Expression<\/a><\/td>\nDr. Dan Stein, Dr. Nastassja Koen, Dr. Kerry Ressler, Dr. Aliza Wingo<\/td>\nSouth Africa<\/td>\n<\/tr>\n
Reprogramming of the Trypanosoma brucei Epigenome during Human Infection: Opportunities for New Therapies<\/a><\/td>\nHugh-George Patterton<\/td>\nSouth Africa<\/td>\n<\/tr>\n
The Nasopharyngeal Microbiome and Respiratory Disease in African Children<\/a><\/td>\nProf. Mark Nicol<\/td>\nSouth Africa<\/td>\n<\/tr>\n
Intergenerational Epigenomics of Trauma and PTSD in Rwanda<\/a><\/td>\nDr. Leon Mutesa, Dr. Monica Uddin, Dr. Derek Wildman, Dr. Stefan Jansen<\/td>\nRwanda, Uganda<\/td>\n<\/tr>\n
Immunoglobulin Gene Diversity in an African Population and Impact Antibody Function in HIV Infection<\/a><\/td>\nProf. Lynn Morris<\/td>\nSouth Africa<\/td>\n<\/tr>\n
DDD-Africa: Deciphering Developmental Disorders in Africa (DDD-Africa) \u2013 Evaluating Clinical Exome Sequencing in an African Setting<\/a><\/td>\nDr. Zane Lombard<\/td>\nSouth Africa, Democratic Republic of the Congo<\/td>\n<\/tr>\n
Clinical and Genetic Studies of Hereditary Neurological Disorders in Mali<\/a><\/td>\nProf. Guida Landoure<\/td>\nMali<\/td>\n<\/tr>\n
Host and Microbial Genetic Determinants of febrile illness in West Africa<\/a><\/td>\nProf. Christian Happi<\/td>\nNigeria<\/td>\n<\/tr>\n
Systems Biology for Molecular Analysis of Tuberculosis in Ethiopia<\/a><\/td>\nProf. Gobena Ameni<\/td>\nEthiopia<\/td>\n<\/tr>\n
RAFAgene: Contribution of genetic variation to pharmacokinetic variability and toxicity in patients undergoing multi-drug tuberculosis treatment in Sub-Saharan Africa<\/a><\/td>\nProf. Dissou Affolabi<\/td>\nBenin, South Africa, Guinea, Senegal<\/td>\n<\/tr>\n
AFBRECANE: African Female Breast Cancer Epidermiology Study<\/a><\/td>\nProf. Clement Adebamowo<\/td>\nNigeria<\/td>\n<\/tr>\n
BEAMING: Breast Milk Microbiota Influence on Infant Immunity and Growth<\/a><\/td>\nDr. Alash\u2019le Abimiku<\/td>\nNigeria, South Africa<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Ethical, Legal, and Society Issues (ELSI) Collaborative Centers” tab_id=”1558346896950-cd11ed3c-c89e”][vc_column_text]<\/p>\n\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
Developing Best Practices of Community Engagement for Genomics and Biobanking in Africa (CEBioGen<\/a>)<\/td>\nGhansah Anita, Tindana Paulina<\/td>\nGhana, Kenya, Nigeria, South Africa<\/td>\n<\/tr>\n
Individual Findings in Genetic Research in Africa (IFGeneRA)<\/a><\/td>\nProf. Ambroise Wonkam, Prof. Jantina de Vries<\/td>\nSouth Africa, Botswana, Cameroon<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”Ethical, Legal, and Society Issues (ELSI) Research Projects” tab_id=”1558347616787-f81a7088-297e”][vc_column_text]<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Project Description<\/th>\nPI Name(s)<\/th>\nLocation<\/th>\n<\/tr>\n
African Neurobiobank for Precision Stroke Medicine \u2013 (ELSI) Project<\/a><\/td>\nDr. Rufus Olusola Akinyemi<\/td>\nNigeria, Ghana<\/td>\n<\/tr>\n
Genetics and Genomic Research in Uganda: Towards Context Specific Ethics Guidelines<\/a><\/td>\nDr. Joseph Ochieng<\/td>\nUganda<\/td>\n<\/tr>\n
Ethical and Social issues in Informed Consent Processes in African Genomic Research<\/a><\/td>\nDr. Erisa Sabakaki<\/td>\nUganda<\/td>\n<\/tr>\n
Stigma in African genomics research on Schizophrenia and Rheumatic Heart Disease<\/a><\/td>\nProf. Jantina de Vries<\/td>\nSouth Africa<\/td>\n<\/tr>\n
Exploring Perspectives on Genomics and Sickle Cell Public Health Interventions<\/a><\/td>\nProf. Ambroise Wonkam<\/td>\nSouth Africa<\/td>\n<\/tr>\n
Enhancing Ethiopian youths\u2019 literacy about the gene x environment contributions to health using the context of Podoconiosis<\/a><\/td>\nProf. Getnet Tadele<\/td>\nEthiopian<\/td>\n<\/tr>\n
Indigenous Linguistic and Cultural Concepts of Heritability and Comprehension of Genomics Research in Africa (INDIGENE) Study<\/a><\/td>\nProf. Clement Adebamowo<\/td>\nNigeria<\/td>\n<\/tr>\n
Genomics Inheritance Legal and Social Issues<\/a><\/td>\nDr Alice Matimba<\/td>\nZimbabwe<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_column_text css_animation=”slideInRight” css=”.vc_custom_1644988965239{margin-top: 36px !important;}”]H3Africa projects have been funded between [\u2026]<\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":46,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":""},"categories":[7,4],"tags":[],"class_list":["post-6155","page","type-page","status-publish","hentry","category-consortium-documents","category-projects"],"_links":{"self":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/6155","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/comments?post=6155"}],"version-history":[{"count":104,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/6155\/revisions"}],"predecessor-version":[{"id":12011,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/6155\/revisions\/12011"}],"up":[{"embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/pages\/46"}],"wp:attachment":[{"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/media?parent=6155"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/categories?post=6155"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/h3africa.org\/index.php\/wp-json\/wp\/v2\/tags?post=6155"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}