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NIH Resources for Applicants and Grantees

When you are preparing to apply for funding please bear in mind that the organisational director, the primary investigator and your institutional unit will be required to undertake a number of pre-registration processes which must be completed before you submit your application for funding. These include: 

  1. Institutional Pre-registration with a number of international bodies which can take a minimum of six weeks.
  2. Setting up an eRA account for the Director or PI/PID.
  3. Registering with eRA Commons in order to receive and transmit information electronically. This can take 2– 4 weeks.
  4. Registering with Grants.gov, which can take eight weeks.

You can click here to download the pdf document of this guidance. Select the section you require from the menu below, or scroll through down the page to access all the information. You can also download some Deanna Ingersol's technical guidance to support your application process as a zipped PowerPoint or a PDF.

I.  NIH "All About Grants" Information and Tutorials

  II.  NIH Grants Policy

  III.  Electronic Submission

  IV.  Research Involving Human Subjects

  V.   Research Involving Animals

 VI.  Additional NIH Resources

       Recommended NIH Listervs


 I. NIH “All About Grants” Information and Tutorials

         NIH All About Grants: https://grants.nih.gov/grants/about_grants.htm

  1. Click on Grants Process Overview to get to the main site, or you might want to watch the video below first.

  2. How to Apply 
  3. Peer Review Process
  4. Award Management  
  5.  Foreign Grants Information

          All About Grants Podcast
          The Office of Extramural Research (OER) talks to NIH staff members about the ins and outs of NIH funding. Designed for investigators, fellows, students, and research administrators.

         NIAID All About Grants Tutorials and Samples: https://www.niaid.nih.gov/researchfunding/grant/pages/aag.aspx 

  • Initiative on Research and Innovation Management (iRIM) - Research Administration Online Tutorials and Presentations. http://researchadministrationtools.org/  . A partnership program funded by the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) and managed by the NIH, Fogarty International Center (FIC) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

 II. NIH Grants Policy

       NIH Grants Policy Statement (NIHGPS) is intended to make available to NIH grantees,
       in a single document, the policy requirements that serve as the terms and conditions of
       NIH grant awards. This document is also designed to be useful to those interested in NIH
       grants by providing information about NIH—its organization, its staff, and its
       grants process.

    NIH Grants Policy Statement (11/15) (NIH GPS):


      Follow this link to find out more about how the NIH approaches funding foreign institutions.

    • Public Policy Requirements and Objectives
    • Funding and Payment
    • Allowable and Unallowable Costs
    • Reporting and Record Retention

 III. Electronic Submission

Required Registration: Electronic submission of grant applications is required for most NIH application types. Applicants from foreign institutions and international organizations must fulfill additional requirements to register for electronic submission of grant applications. Registration can be a lengthy process and foreign organizations are especially encouraged to register early.

Applicant Organizations: Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible.

The NIH Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a late submission.

        1. Dun and Bradstreet Universal Numbering System (DUNS) - All registrations require that applicants be issued a DUNS number. After obtaining a DUNS number, applicants can begin both SAM and eRA Commons registrations. The same DUNS number must be used for all registrations, as well as on the grant application.
        2. System for Award Management (SAM) (formerly CCR) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code.
        3. NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.
        4. eRA Commons – This is the NIH electronic Research Administration system that allows applicants/grantees to electronically receive and transmit application and award information. All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Applicants must have an active DUNS number and SAM registration in order to complete the eRA Commons registration. Organizations can register with the eRA Commons as they are working through their SAM or Grants.gov registration.
        5. Grants.gov – This is the U.S. Federal government’s single online portal to find and apply for Federal funding.  Applicants must have an active DUNS number and SAM registration in order to complete the Grants.gov registration. Institutions and the Authorized Organization Representative (AOR) should register on Grants.gov.

     For more on the NIH Submission Process you may find these links useful: 

NIH eSubmission Tips:


 IV. Research Involving Human Subjects: 

 V. Research Involving Animals: http://grants.nih.gov/grants/policy/air/

 VI. Additional NIH Resources:


  Recommended NIH Listservs


General Grants Information
Phone: 301-435-0714
Fax: 301-480-0525
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Hours: Monday-Friday 8:30 a.m. to 5 p.m. EST
Contact for assistance with: 

        •  Finding grant-related information, resources, guidelines, and contacts
        • Identifying grant programs
        • General questions about the electronic submission process and application forms, and the review and award processes

Dun & Bradstreet (DUNS)
Toll-free: 1-866-705-5711
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
URL: http://fedgov.dnb.com/webform

Contact for assistance with: Obtaining a DUNS number (required for CCR and Grants.gov registration)

North Atlantic Treaty Organization (NATO) Commercial and Government Entity (CAGE) = NCAGE Code
Toll Free: 1-888-227-2423
International: 269-961-7766
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Contact for assistance with: Obtaining an NCAGE code (required for CCR registration)

System for Award Management (SAM)
Fed Info: 1-800-FED-INFO
Toll Free: 866-606-8220
International: 334-206-7828
Web: https:www.fsd.gov
Hours: Monday-Friday 8:00 a.m. to 8:00 p.m. EST
URL: http://www.sam.gov

Contact for assistance with:

        • Registering your organization
        • Registering your e-Business Point of Contact
        • Renewal of entity registration and information update

eRA Service Desk (formerly the eRA Commons Help Desk): http://grants.nih.gov/support/

Toll-free: 1-866-504-9552
Phone: 301-402-7469
Hours: Mon-Fri, 7:00a.m. to 8:00p.m. U.S.Eastern Time (closed on federal holidays)

Contact for information/questions on:

        • ASSIST
        • eRA Commons
        • eRA Commons Registration
        • eRA errors and warnings
        • Status of the application
        • Post-award administration
        • Grants.gov Contact Center

International: 606-545-5035
Toll-free: 1-800-518-4726
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Hours: 24 hours a day, 7 days a week (closed on Federal Holidays)
Web ticketing/live chat: https://grants-portal.psc.gov/Welcome.aspx?pt=Grants
Contact for assistance with:

      • Grants.gov Registration
      • Downloading or navigating forms
      • Technical aspects of submitting to the Grants.gov system