“There is currently a global effort to apply genomic science and associated technologies to further the understanding of health and disease in diverse populations. These efforts work to identify individuals and populations who are at risk for developing specific diseases, and to better understand underlying genetic and environmental contributions to that risk. Given the large amount of genetic diversity on the African continent, there exists an enormous opportunity to utilize such approaches to benefit African populations and to inform global health.

The Human Heredity and Health in Africa (H3Africa) consortium facilitates fundamental research into diseases on the African continent while also developing infrastructure, resources, training, and ethical guidelines to support a sustainable African research enterprise – led by African scientists, for the African people. The initiative consists of 48 African projects that include population-based genomic studies of common, non-communicable disorders such as heart and renal disease, as well as communicable diseases such as tuberculosis. These studies are led by African scientists and use genetic, clinical, and epidemiologic methods to identify hereditary and environmental contributions to health and disease. To establish a foundation for African scientists to continue this essential work into the future work, the consortium also supports many crucial capacity building elements, such as: ethical, legal, and social implications research; training and capacity building for bioinformatics; capacity for biobanking; and coordination and networking.

H3Africa empowers African researchers to be competitive in genomic sciences, establishes and nurtures effective collaborations among African researchers on the African continent and generates unique data that could be used to improve African and indeed global health

$170million

Overall monetary investment by NIH/Wellcome Trust

+500

Consortium Members

180

Study Coordinators/Community Engagement Representatives/Fellows Travel supported

27

Workshops/Themed meetings (H3Africa Only)

48

H3Africa Projects supported

1026

Number of Workshop/Satellite meeting attendees - H3Africa Only

61

Number of BSc

335

Number of members registered on the HtrainDB

382

Trainees

54000

Research Participants Recruited

34

African Countries involved

331

Number of members accessing the Digest on HtrainDB

2062

Number of Workshop/Satellite meeting attendees (Including H3ABioNet)

193

Number of PhD

197

H3Africa Publications

127

Number of MSc

53

Number of Workshops/Themed meetings (Including H3ABioNet)

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