DBAC Approvals


NameInstitution/Research GroupStudyDatasets
Prof JM HeckmannUniversity of Capetown, South AfricaInvestigating the genetic basis of amyotrophic lateral sclerosis (ALS) and other neuromuscular disorders in South AfricansTrypanoGEN and H3ABaylor WGS datasets:
H3AChip-TrypanoGEN 2 EGAD00001004220
H3AChip-AWI-Gen EGAD00001004448
H3AChip-TrypanoGEN 1 EGAD00001004393
H3AChip-ELSI EGAD00001004316
H3AChip-CAfGEN EGAD00001004533
H3AChip-ACCME EGAD00001004505
H3AChip-NEEDI EGAD00001004334
H3AChip-MalSic EGAD00001004557
TrypanoGEN Main EGAD00001005076
AWI-Gen Phase 1 WGS data from 100 South Africans EGAD00001006418
Prof Carina SchlebuschUppsala University, Evolutionary Biology Centre, SwedenA genomic perspective on the history of AfricaH3A-Baylor and TrypanoGEN WGS datasets:
H3AChip-TrypanoGEN 2 EGAD00001004220
H3AChip-AWI-Gen EGAD00001004448
H3AChip-TrypanoGEN 1 EGAD00001004393
H3AChip-ELSI EGAD00001004316
H3AChip-CAfGEN EGAD00001004533
H3AChip-ACCME EGAD00001004505
H3AChip-NEEDI EGAD00001004334
H3AChip-MalSic EGAD00001004557
TrypanoGEN Main EGAD00001005076
Prof Christof R. HauckKonstanz University, GermanyCEACAM polymorphisms and their role for bacterial adhesin bindingWES/WGS:
CAfGEN Exome EGAD00001006224
TrypanoGEN Main EGAD00001005076
Maria Chahrour, Ph.D.University of Texas Southwestern Medical Center,
United States
The genetics of neurodevelopmental disordersH3AChip data:
H3AChip-Trypanogen 2 EGAD00001004220;
H3AChip-Awi-gen EGAD00001004448;
H3AChip-Elsi EGAD00001004316;
H3AChip-Trypanogen 1 EGAD00001004393;
H3AChip-Cafgen EGAD00001004533;
H3AChip-Accme EGAD00001004505;
H3AChip-Needi EGAD00001004334;
H3AChip-Malsic EGAD00001004557.
Alicia Martin, Ph.DBroad Institute, Massachusetts, United StatesDeveloping a population genetic and imputation resource of diverse human genomesWGS datasets:
H3AChip-Phenotype EGAD00001005310;
AWI-Gen Phase 1 GWAS Genotype EGAD00010001996;
AWI-Gen Phase 1 WGS data from 100 South Africans EGAD00001006418;
H3AChip-Trypanogen 2 EGAD00001004220; H3AChip-Awi-gen EGAD00001004448;
H3AChip-Elsi EGAD00001004316;
H3AChip-Trypanogen 1 EGAD00001004393; H3AChip-Cafgen EGAD00001004533;
H3AChip-Accme EGAD00001004505;
H3AChip-Needi EGAD00001004334;
H3AChip-Malsic EGAD00001004557
Dr Jana VandrovcovaUniversity College London, United KingdomThe International Centre for Genomic Medicine in Neuromuscular Disease (ICGNMD)WGS/WES datasets:
AWI-Gen Phase 1 GWAS Genotype EGAD00010001996
AWI-Gen Phase 1 WGS data from 100 South Africans EGAD00001006418
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Elsi EGAD00001004316
H3AChip-Trypanogen 1 EGAD00001004393
H3AChip-Cafgen EGAD00001004533
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
NEEDI SNPs and INDELS EGAD00001006295
CAfGEN Exome EGAD00001006224
H3AChip-Malsic EGAD00001004557
TrypanoGEN Main EGAD00001005076
AWI-Gen Pilot EGAD00010001258
Prof Michael PepperUniversity of Pretoria, South AfricaTo determine the African variant allele frequencies and predicted variant effects of
genes associated with neonatal encephalopathy with suspected hypoxic-ischemic encephalopathy
(NESHIE), Coronavirus disease 2019 (COVID-19), cystic fibrosis and cardiometabolic diseases
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Elsi EGAD00001004316
H3AChip-Trypanogen 1 EGAD00001004393
H3AChip-Cafgen EGAD00001004533
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
CAfGEN Exome EGAD00001006224
H3AChip-Malsic EGAD00001004557
TrypanoGEN Main EGAD00001005076
Dr Sandra BelezaUniversity of Leicester, United KingdomWhole Genome Sequencing of Populations from Cabinda, Angola and Maputo, MozambiqueH3AChip data
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Elsi EGAD00001004316
H3AChip-Trypanogen 1 EGAD00001004393
H3AChip-Cafgen EGAD00001004533
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
H3AChip-Malsic EGAD00001004557
H3AChip-AWI-Gen EGAD00001004448
Prof Ezekiel AdebiyiCovenant University Ota, Ogun State, NigeriaGenome-wide characterization of complex variants and their phenotypic effects in African populationsWGS datasets:
H3AChip-Elsi EGAD00001004316
NEEDI SNPs and INDELS EGAD00001006295
H3AChip-Malsic EGAD00001004557
H3AChip-Trypanogen 1 EGAD00001004393
AWI-Gen Phase 1 GWAS Genotype EGAD00010001996
H3AChip-Needi EGAD00001004334
CAfGEN Exome EGAD00001006224
AWI-Gen Pilot EGAD00010001258
TrypanoGEN Main EGAD00001005076
H3AChip-Phenotype EGAD00001005310
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Cafgen EGAD00001004533
AWI-Gen Phase 1 Phenotype EGAD00001006425
AWI-Gen Phase 1 Pilot Microbiome PRJEB40733
AWI-Gen Phase 1 Pilot Microbiome Phenotype EGAD00001006581
AWI-Gen Phase 1 WGS data from 100 South Africans EGAD00001006418
H3Africa Consortium WGS VCF EGAD00001008577
Dr Carla Marquez-LunaMartingale Labs, Brooklyn, United StatesEvaluating the utility of current clinical genetic testing methods across diverse populationsWGS datasets:
H3Africa Consortium WGS VCF EGAD00001008577
Prof Michael PepperUniversity of Pretoria, South AfricaA multi-variate, multi-omics study on the pathogenesis of moderate-severe neonatal encephalopathy with suspected hypoxic ischemic encephalopathyDatasets:
H3AChip-Elsi EGAD00001004316
H3AChip-Malsic EGAD00001004557
H3AChip-Trypanogen 1 EGAD00001004393
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
CAfGEN Exome EGAD00001006224
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Cafgen EGAD00001004533
H3Africa Consortium WGS VCF EGAD00001008577
Dr Catherine TcheandjieuUniversity of California San Francisco, California, USAUnderstanding the 9p21.3 coronary artery disease-risk regionWGS, SNP array, and phenotype datasets:
AWI-Gen Phase 1 GWAS Genotype EGAD00010001996
AWI-Gen Phase 1 Phenotype EGAD00001006425
H3Africa Consortium WGS VCF EGAD00001008577
Dr Houcemeddine OthmanUniversity of the Witwatersrand, Johannesburg, South AfricaAn integrative data-driven approach to the genomics of anti-tuberculosis and anti-malarial drug responses in African populations: The AGORA-TM projectWGS datasets:
H3Africa Consortium WGS VCF EGAD00001008577
Dr Hongsheng GuiMichigan State University Health Sciences,
United States
Pharmacoepidemiology and pharmacogenomics of opioid use and use disorder during COVID pandemicWGS datasets:
H3Africa Consortium WGS VCF EGAD00001008577
Etienne Patin, PhDInstitut Pasteur, FranceThe impact of recent demographic changes on the genetic architecture of complex diseases in Central AfricansWGS datasets:
H3AChip-Elsi EGAD00001004316
H3AChip-Malsic EGAD00001004557
H3AChip-Trypanogen 1 EGAD00001004393
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Cafgen EGAD00001004533
Prof Vanessa DumeauxThe University of Western Ontario, CanadaFunctional Interactions and Global Diversity in Gut Microbiomes: Advancing Microbial Community Type Identification with Deep Learning ApproachesAWI-Gen Phase 1 Pilot Microbiome Phenotype EGAD00001006581
Prof Yukinori OkadaOsaka University Graduate School of Medicine, JapanElucidation of disease pathology by multi-omics analysis of the homogeneity and heterogeneity of selection signatures in diverse populationsWGS datasets:
H3AChip-Elsi EGAD00001004316
H3AChip-Malsic EGAD00001004557
H3AChip-Trypanogen 1 EGAD00001004393
AWI-Gen Phase 1 GWAS Genotype EGAD00010001996
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
AWI-Gen Pilot EGAD00010001258
TrypanoGEN Main EGAD00001005076
ACCME NIH H3Africa phs001945.v1.p1
H3AChip-Phenotype EGAD00001005310
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Cafgen EGAD00001004533
AWI-Gen Phase 1 Phenotype EGAD00001006425
ReMAC-Phenotype EGAD00001006244
AWI-Gen Phase 1 WGS data from 100 South Africans EGAD00001006418
H3Africa Consortium WGS VCF EGAD00001008577
Dr Mahmoud AarabiUniversity of Pittsburgh, United StatesCarrier frequency of autosomal recessive conditions in African populationWGS data
TrypanoGEN Main EGAD00001005076
Prof David CurtisUniversity College London, United KingdomDistribution of genetic variants across human populationsAWI-Gen Phase 1 GWAS Genotype EGAD00010001996
H3Africa Consortium WGS VCF EGAD00001008577
Dr David TwesigomweUniversity of the Witwatersrand, South AfricaCharacterisation of pharmacogene allelic variation in African populations and development of a novel diplotype calling algorithm: Phase 2WGS and WES datasets:
H3AChip-Elsi EGAD00001004316
H3AChip-Malsic EGAD00001004557
H3AChip-Trypanogen 1 EGAD00001004393
H3AChip-Accme EGAD00001004505
H3AChip-Needi EGAD00001004334
CAfGEN Exome EGAD00001006224
H3AChip-Trypanogen 2 EGAD00001004220
H3AChip-Awi-gen EGAD00001004448
H3AChip-Cafgen EGAD00001004533
AWI-Gen Phase 1 WGS data from 100 South Africans EGAD00001006418
Tabitha OslerUniversity of the Witwatersrand, South AfricaPrevalence and consequences of variants in genes associated with breast cancer in black South African womenWGS datasets:
TrypanoGEN Main EGAD00001005076
H3Africa Consortium WGS VCF EGAD00001008577