Genetic risk scores could predict disease in Africans
– Wits University
Using genetic risk scores to predict which individuals have a higher risk genetically of developing a particular disease is set to revolutionise medicine.
The genetic risk scores (GRS) approach to predicting disease risk enables early detection and treatment in a personalised way.
GRS has shown significant progress and potential in European populations. However, applying the approaches developed from European data to African populations shows that GRS are 4.5 times less accurate. This is partly due to the fact that people of African ancestry account for only 1.1% of the global participants in genomic studies.