H3Africa Publications for 2021
- Human microbiota research in Africa: a systematic review reveals gaps and priorities for future research. Allali I, Abotsi RE, Tow LA, Thabane L, Zar HJ, Mulder NM, Nicol MP. Microbiome. 2021 Dec 15;9(1):241. doi: 10.1186/s40168-021-01195-7. Erratum in: Microbiome. 2022 Jan 19;10(1):10. PMID: 34911583; PMCID: PMC8672519.
- Ten simple rules for developing bioinformatics capacity at an academic institution. Aron S, Jongeneel CV, Chauke PA, Chaouch M, Kumuthini J, Zass L, Radouani F, Kassim SK, Fadlelmola FM, Mulder N. PLoS Comput Biol. 2021 Dec 9;17(12):e1009592. doi: 10.1371/journal.pcbi.1009592. PMID: 34882684; PMCID: PMC8659687.
- Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Ansari-Pour N, Zheng Y, Yoshimatsu TF, Sanni A, Ajani M, Reynier JB, Tapinos A, Pitt JJ, Dentro S, Woodard A, Rajagopal PS, Fitzgerald D, Gruber AJ, Odetunde A, Popoola A, Falusi AG, Babalola CP, Ogundiran T, Ibrahim N, Barretina J, Van Loo P, Chen M, White KP, Ojengbede O, Obafunwa J, Huo D, Wedge DC, Olopade OI. Nat Commun. 2021 Nov 26;12(1):6946. doi: 10.1038/s41467-021-27079-w. PMID: 34836952; PMCID: PMC8626467.
- Chapter 9 The H3Africa Consortium: Publication Outputs of a Pan-African Genomics Collaboration (2013 to 2020). In Africa, the Cradle of Human Diversity. Choudhury, A., Sengupta, D., Aron, S., & Ramsay, M. (2021). Leiden, The Netherlands: Brill. doi: https://doi.org/10.1163/9789004500228_011
- A Monoallelic Variant in REST Is Associated with Non-Syndromic Autosomal Dominant Hearing Impairment in a South African Family. Manyisa, N., Schrauwen, I., De Souza Rios, L.A., Mowla, S., Tekendo-Ngongang, C., Popel, K., Esoh, K., Bharadwaj, T., Nouel-Saied, L.M., Acharya, A., Nasir, A., Wonkam-Tingang, E., Kock, C.D., Dandara, C., Leal, S.M., Wonkam, A., 2021. Genes 12, 1765.. doi:10.3390/genes12111765
- A novel variant in DMXL2 gene is associated with autosomal dominant non-syndromic hearing impairment (DFNA71) in a Cameroonian family. Wonkam-Tingang E, Schrauwen I, Esoh KK, Bharadwaj T, Nouel-Saied LM, Acharya A, Nasir A, Leal SM, Wonkam A. Exp Biol Med (Maywood). 2021 Jul;246(13):1524-1532. doi: 10.1177/1535370221999746. Epub 2021 Mar 9. Erratum in: Exp Biol Med (Maywood). 2021 Nov;246(21):NP5. PMID: 33715530; PMCID: PMC8283254.
- Profiling of warfarin pharmacokinetics-associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics-dosing algorithm. Ndadza A, Muyambo S, Mntla P, Wonkam A, Chimusa E, Kengne AP, Ntsekhe M, Dandara C. P. J Thromb Haemost. 2021 Aug 12. doi: 10.1111/jth.15494. Epub ahead of print. PMID: 34382722.
- Utilization of Pneumococcal Vaccine and Penicillin Prophylaxis in Sickle Cell Disease in Three African Countries: Assessment among Healthcare Providers in SickleInAfrica. Brown BJ, Madu A, Sangeda RZ, Nkya S, Peprah E, Paintsil V, Mmbando BP, Gyamfi J, Okocha CE, Asala SA, Nembaware V, Jonas M, Kengne AP, Chimusa ER, Nguweneza A, Isa HA, Nnebe-Agumadu U, Adekile AD, Osei-Akoto A, Ohene-Frempong K, Balandya E, Nnodu OE, Wonkam A, Makani J; SickleInAfrica Consortium. Hemoglobin. 2021 May;45(3):163-170. doi: 10.1080/03630269.2021.1954943. Epub 2021 Aug 6. PMID: 34355623.
- Implementation science research for the scale-up of evidence-based interventions for sickle cell disease in africa: a commentary. Gyamfi J, Ojo T, Iwelunmor J, Ogedegbe G, Ryan N, Diawara A, Nnodu O, Wonkam A, Royal C, Peprah E. Global Health. 2021 Feb 17;17(1):20. doi: 10.1186/s12992-021-00671-x. PMID: 33596947; PMCID: PMC7888072.
- Negotiating political power and stigma around fragile X Syndrome in a rural village in Cameroon: A tale of a royal family and a community. Kengne Kamga K, Munung NS, Nguefack S, Wonkam A, De Vries J. Mol Genet Genomic Med. 2021 Mar;9(3):e1615. doi: 10.1002/mgg3.1615. Epub 2021 Feb 5. PMID: 33544459; PMCID: PMC8104168.
- Participants’ Preferences and Reasons for Wanting Feedback of Individual Genetic Research Results From an HIV-TB Genomic Study: A Case Study From Botswana. Ralefala D, Kasule M, Matshabane OP, Wonkam A, Matshaba M, de Vries J. J Empir Res Hum Res Ethics. 2021 Dec;16(5):525-536. doi: 10.1177/15562646211043985. PMID: 34662218.
- The International Hemoglobinopathy Research Network (INHERENT): An international initiative to study the role of genetic modifiers in hemoglobinopathies. Kountouris P, Stephanou C, Archer N, Bonifazi F, Giannuzzi V, Kuo KHM, Maggio A, Makani J, Mañú-Pereira MDM, Michailidou K, Nkya S, Nnodu OE, Trompeter S, Tshilolo L, Wonkam A, Zilfalil BA, Inusa BPD, Kleanthous M; on behalf of the International Hemoglobinopathy Research Network (INHERENT). Am J Hematol. 2021 Nov 1;96(11):E416-E420. doi: 10.1002/ajh.26323. Epub 2021 Aug 30. PMID: 34406671.
- Investigations of Kidney Dysfunction-Related Gene Variants in Sickle Cell Disease Patients in Cameroon (Sub-Saharan Africa). Ngo-Bitoungui VJ, Belinga S, Mnika K, Masekoameng T, Nembaware V, Essomba RG, Ngo-Sack F, Awandare G, Mazandu GK, Wonkam A. Front Genet. 2021 Mar 15;12:595702. doi: 10.3389/fgene.2021.595702. PMID: 33790942; PMCID: PMC8005585.
- Rationale and design of the African Cardiomyopathy and Myocarditis Registry Program: The IMHOTEP study. Kraus SM, Shaboodien G, Francis V, Laing N, Cirota J, Chin A, Pandie S, Lawrenson J, Comitis GAM, Fourie B, Zühlke L, Wonkam A, Wainwright H, Damasceno A, Mocumbi AO, Pepeta L, Moeketsi K, Thomas BM, Thomas K, Makotoko M, Brown S, Ntsekhe M, Sliwa K, Badri M, Gumedze F, Cordell HJ, Keavney B, Ferreira V, Mahmod M, Cooper LT, Yacoub M, Neubauer S, Watkins H, Mayosi BM, Ntusi NAB; IMHOTEP Investigators. Int J Cardiol. 2021 Jun 15;333:119-126. doi: 10.1016/j.ijcard.2021.02.026. Epub 2021 Feb 16. PMID: 33607192.
- Systematic Review of the Economic Evaluation of Returning Incidental Findings in Genomic Research. Fontes Marx M, Ataguba JE, de Vries J, Wonkam A. Front Public Health. 2021 Jul 1;9:697381. doi: 10.3389/fpubh.2021.697381. PMID: 34277554; PMCID: PMC8281014.
- Explanatory models for the cause of Fragile X Syndrome in rural Cameroon. Kengne Kamga K, De Vries J, Nguefack S, Munung NS, Wonkam A. J Genet Couns. 2021 Jun 17. doi: 10.1002/jgc4.1440. Epub ahead of print. PMID: 34145661.
- Further confirmation of the association of SLC12A2 with non-syndromic autosomal-dominant hearing impairment. Adadey SM, Schrauwen I, Aboagye ET, Bharadwaj T, Esoh KK, Basit S, Acharya A, Nouel-Saied LM, Liaqat K, Wonkam-Tingang E, Mowla S, Awandare GA, Ahmad W, Leal SM, Wonkam A. FJ Hum Genet. 2021 Jul 5. doi: 10.1038/s10038-021-00954-6. Epub ahead of print. PMID: 34226616.
- Whole exome sequencing reveals pathogenic variants in MYO3A, MYO15A and COL9A3 and differential frequencies in ancestral alleles in hearing impairment genes among individuals from Cameroon. Wonkam A, Manyisa N, Bope CD, Dandara C, Chimusa ER. Hum Mol Genet. 2021 Feb 4;29(23):3729-3743. doi: 10.1093/hmg/ddaa225. PMID: 33078831; PMCID: PMC7861016.
- “Pain is Subjective”: A Mixed-Methods Study of Provider Attitudes and Practices Regarding Pain Management in Sickle Cell Disease Across Three Countries. Stewart KA, Parshad-Asnani M, Wonkam A, Bollinger J, Ngo Bitoungui V, Wonkam-Tingang E, Powell J, Desronvil K, Benson KRK, Clark A, Katz M, Martin B, Peterseim C, Williams C, Young N, Shah N, Tanabe P, Babyak M, Royal CDM. J Pain Symptom Manage. 2021 Mar;61(3):474-487. doi: 10.1016/j.jpainsymman.2020.08.029. Epub 2020 Sep 1. PMID: 32889040.
- Whole exome sequencing identifies rare coding variants in novel human-mouse ortholog genes in African individuals diagnosed with non-syndromic hearing impairment. Oluwole OG, Esoh KK, Wonkam-Tingang E, Manyisa N, Noubiap JJ, Chimusa ER, Wonkam A. Exp Biol Med (Maywood). 2021 Jan;246(2):197-206. doi: 10.1177/1535370220960388. Epub 2020 Sep 30. PMID: 32996353; PMCID: PMC7871117.
- Sickle cell disease in sub-Saharan Africa: transferable strategies for prevention and care. Esoh K, Wonkam-Tingang E, Wonkam A. Lancet Haematol. 2021 Oct;8(10):e744-e755. doi: 10.1016/S2352-3026(21)00191-5. Epub 2021 Sep 2. PMID: 34481550.
- Modelling the mortality of sickle cell disease in Africa. Wonkam A, Kengne AP. Lancet Haematol. 2021 Oct;8(10):e677-e678. doi: 10.1016/S2352-3026(21)00268-4. Epub 2021 Sep 2. PMID: 34481548.
- Collect more data from Africa to improve gene therapy. Wonkam A. Nature. 2021 Aug;596(7873):S5. doi: 10.1038/d41586-021-02139-9. PMID: 34433952.
- Hearing loss in Africa: current genetic profile. Adadey SM, Wonkam-Tingang E, Aboagye ET, Quaye O, Awandare GA, Wonkam A. Hum Genet. 2021 Oct 5. doi: 10.1007/s00439-021-02376-y. Epub ahead of print. PMID: 34609590.
- Evolutionary history of sickle-cell mutation: implications for global genetic medicine. Esoh K, Wonkam A. Hum Mol Genet. 2021 Apr 26;30(R1):R119-R128. doi: 10.1093/hmg/ddab004. PMID: 33461216; PMCID: PMC8117455.
- “Iron”ing out hemophagocytosis through PIEZO1. Hanchard NA, Wonkam A. Cell. 2021 Feb 18;184(4):856-858. doi: 10.1016/j.cell.2021.01.038. PMID: 33606984.
- Dementia in Africa: Current evidence, knowledge gaps, and future directions. Akinyemi RO, Yaria J, Ojagbemi A, Guerchet M, Okubadejo N, Njamnshi AK, Sarfo FS, Akpalu A, Ogbole G, Ayantayo T, Adokonou T, Paddick SM, Ndetei D, Bosche J, Ayele B, Damas A, Coker M, Mbakile-Mahlanza L, Ranchod K, Bobrow K, Anazodo U, Damasceno A, Seshadri S, Pericak-Vance M, Lawlor B, Miller BL, Owolabi M, Baiyewu O, Walker R, Gureje O, Kalaria RN, Ogunniyi A; African Dementia Consortium (AfDC). Alzheimers Dement. 2021 Sep 27. doi: 10.1002/alz.12432. Epub ahead of print. PMID: 34569714.
- Stroke in Africa: profile, progress, prospects and priorities. Akinyemi RO, Ovbiagele B, Adeniji OA, Sarfo FS, Abd-Allah F, Adoukonou T, Ogah OS, Naidoo P, Damasceno A, Walker RW, Ogunniyi A, Kalaria RN, Owolabi MO. Nat Rev Neurol. 2021 Oct;17(10):634-656. doi: 10.1038/s41582-021-00542-4. Epub 2021 Sep 15. PMID: 34526674; PMCID: PMC8441961.
- Strategies for Reducing Non-Communicable Diseases in Africa. Olowoyo P, Popoola F, Yaria J, Akinyemi R, Maffia P, Owolabi MO. Pharmacol Res. 2021 Aug;170:105736. doi: 10.1016/j.phrs.2021.105736. Epub 2021 Jun 17. PMID: 34147659.
- The Development of a Sustainable Bioinformatics Training Environment Within the H3Africa Bioinformatics Network (H3ABioNet). Aron Shaun, Chauke Paballo Abel, Ras Verena, Panji Sumir, Johnston Katherine, Mulder Nicola. Frontiers in Education doi: 10.3389/feduc.2021.725702
- HIV Viremia Is Associated With APOL1 Variants and Reduced JC-Viruria. Kruzel-Davila E, Sankofi BM, Kubi Amos-Abanyie E, Ghansah A, Nyarko A, Agyemang S, Awandare GA, Szwarcwort-Cohen M, Reiner-Benaim A, Hijazi B, Ulasi I, Raji YR, Boima V, Osafo C, May Adabayeri V, Matekole M, Olanrewaju TO, Ajayi S, Mamven M, Antwi S, Ademola AD, Plange-Rhule J, Arogundade F, Akyaw PA, Winkler CA, Salako BL, Ojo A, Skorecki K, Adu D. Front Med (Lausanne). 2021 Aug 27;8:718300. doi: 10.3389/fmed.2021.718300. PMID: 34513880; PMCID: PMC8429812.
- African Global Representation in Biomedical Sciences. Mulder N, Zass L, Hamdi Y, Othman H, Panji S, Allali I, Fakim YJ. Annu Rev Biomed Data Sci. 2021 Jul 20;4:57-81. doi: 10.1146/annurev-biodatasci-102920-112550. PMID: 34465182.
- Wilkinson, E., et al. “A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa.” Science 0(0): eabj4336.
- SickleGenAfrica Network. Sickle Cell Disease Genomics of Africa (SickleGenAfrica) Network: ethical framework and initial qualitative findings from community engagement in Ghana, Nigeria and Tanzania. Anie KA, Olayemi E, Paintsil V, Owusu-Dabo E, Adeyemo TA, Sani MU, Galadanci NA, Nnodu O, Tluway F, Adjei DN, Mensah P, Sarfo-Antwi J, Nwokobia H, Gambo A, Benjamin A, Salim A, Osae-Larbi JA, Ofori-Acquah SF; BMJ Open. 2021 Jul 23;11(7):e048208. doi: 10.1136/bmjopen-2020-048208. PMID: 34301659; PMCID: PMC8311318.
- Metabolic Traits and Stroke Risk in Individuals of African Ancestry: Mendelian Randomization Analysis. Fatumo S, Karhunen V, Chikowore T, Sounkou T, Udosen B, Ezenwa C, Nakabuye M, Soremekun O, Daghlas I, Ryan DK, Taylor A, Mason AM, Damrauer SM, Vujkovic M, Keene KL, Fornage M, Järvelin MR, Burgess S, Gill D. Stroke. 2021 Aug;52(8):2680-2684. doi: 10.1161/STROKEAHA.121.034747. Epub 2021 Jun 3. PMID: 34078102; PMCID: PMC8312569.
- Further confirmation of the association of SLC12A2 with non-syndromic autosomal-dominant hearing impairment. Adadey SM, Schrauwen I, Aboagye ET, Bharadwaj T, Esoh KK, Basit S, Acharya A, Nouel-Saied LM, Liaqat K, Wonkam-Tingang E, Mowla S, Awandare GA, Ahmad W, Leal SM, Wonkam A. J Hum Genet. 2021 Jul 5. doi: 10.1038/s10038-021-00954-6. Epub ahead of print. PMID: 34226616.
- Systematic Review of the Economic Evaluation of Returning Incidental Findings in Genomic Research. Fontes Marx M, Ataguba JE, de Vries J, Wonkam A. Front Public Health. 2021 Jul 1;9:697381. doi: 10.3389/fpubh.2021.697381. PMID: 34277554; PMCID: PMC8281014.
- Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Mali: a systematic review and meta-analysis. Maiga FO, Wele M, Toure SM, Keita M, Tangara CO, Refeld RR, Thiero O, Kayentao K, Diakite M, Dara A, Li J, Toure M, Sagara I, Djimdé A, Mather FJ, Doumbia SO, Shaffer JG. Malar J. 2021 Aug 30;20(1):356. doi: 10.1186/s12936-021-03890-0. PMID: 34461901; PMCID: PMC8404312.
- Molecular surveillance of shiga toxigenic Escherichia coli in selected beef abattoirs in Osun State Nigeria. Ayoade F, Oguzie J, Eromon P, Omotosho OE, Ogunbiyi T, Olumade T, Akano K, Folarin O, Happi C. Sci Rep. 2021 Jul 7;11(1):13966. doi: 10.1038/s41598-021-93347-w. PMID: 34234223; PMCID: PMC8263744.
- Whole-genome sequencing of SARS-CoV-2 in Uganda: implementation of the low-cost ARTIC protocol in resource-limited settings. Mboowa G, Mwesigwa S, Kateete D, Wayengera M, Nasinghe E, Katagirya E, Katabazi AF, Kigozi E, Kirimunda S, Kamulegeya R, Kabahita JM, Luutu MN, Nabisubi P, Kanyerezi S, Bagaya BS, Joloba ML. F1000Res. 2021 Jul 19;10:598. doi: 10.12688/f1000research.53567.1. PMID: 34457243; PMCID: PMC8378408.
- Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Fatumo S, Chikowore T, Kalyesubula R, Nsubuga RN, Asiki G, Nashiru O, Seeley J, Crampin AC, Nitsch D, Smeeth L, Kaleebu P, Burgess S, Nyirenda M, Franceschini N, Morris AP, Tomlinson L, Newton R. Hum Mol Genet. 2021 Jul 28;30(16):1559-1568. doi: 10.1093/hmg/ddab088. PMID: 33783510; PMCID: PMC8330895.
- Antennal Enriched Odorant Binding Proteins Are Required for Odor Communication in Glossina f. fuscipes. Diallo S, Shahbaaz M, Makwatta JO, Muema JM, Masiga D, Christofells A, Getahun MN. Biomolecules. 2021 Apr 8;11(4):541. doi: 10.3390/biom11040541. PMID: 33917773; PMCID: PMC8068202.
- Estimating the burden of cardiovascular risk in community dwellers over 40 years old in South Africa, Kenya, Burkina Faso and Ghana. Wagner RG, Crowther NJ, Micklesfield LK, Boua PR, Nonterah EA, Mashinya F, Mohamed SF, Asiki G, Tollman S, Ramsay M, Davies JI. BMJ Glob Health. 2021 Jan;6(1):e003499. doi: 10.1136/bmjgh-2020-003499. PMID: 33479017; PMCID: PMC7825268.
- New neural network classification method for individuals ancestry prediction from SNPs data. Soumare H, Rezgui S, Gmati N, Benkahla A. BioData Min. 2021 Jun 28;14(1):30. doi: 10.1186/s13040-021-00258-7. PMID: 34183066; PMCID: PMC8240223.
- Reviewing and assessing existing meta-analysis models and tools. Makinde FL, Tchamga MSS, Jafali J, Fatumo S, Chimusa ER, Mulder N, Mazandu GK. Brief Bioinform. 2021 Aug 20:bbab324. doi: 10.1093/bib/bbab324. Epub ahead of print. PMID: 34415019.
- Diversity in immunogenomics: the value and the challenge. Peng K, Safonova Y, Shugay M, Popejoy AB, Rodriguez OL, Breden F, Brodin P, Burkhardt AM, Bustamante C, Cao-Lormeau VM, Corcoran MM, Duffy D, Fuentes-Guajardo M, Fujita R, Greiff V, Jönsson VD, Liu X, Quintana-Murci L, Rossetti M, Xie J, Yaari G, Zhang W, Abedalthagafi MS, Adekoya KO, Ahmed RA, Chang WC, Gray C, Nakamura Y, Lees WD, Khatri P, Alachkar H, Scheepers C, Watson CT, Karlsson Hedestam GB, Mangul S. Nat Methods. 2021 Jun;18(6):588-591. doi: 10.1038/s41592-021-01169-5. PMID: 34002093.
- Ten simple rules for organizing a bioinformatics training course in low- and middle-income countries. Moore B, Carvajal-López P, Chauke PA, Cristancho M, Dominguez Del Angel V, Fernandez-Valverde SL, Ghouila A, Gopalasingam P, Guerfali FZ, Matimba A, Morgan SL, Oliveira G, Ras V, Reyes A, De Las Rivas J, Mulder N. PLoS Comput Biol. 2021 Aug 19;17(8):e1009218. doi: 10.1371/journal.pcbi.1009218. PMID: 34411091; PMCID: PMC8375989.
- Frequency and factors associated with post-stroke seizures in a large multicenter study in West Africa. Sarfo FS, Akinyemi J, Akpalu A, Wahab K, Yaria J, Adebayo O, Komolafe M, Obiako R, Owolabi L, Osaigbovo GO, Jenkins C, Mensah Y, Ogbole G, Calys-Tagoe B, Adebayo P, Appiah L, Singh A, Fakunle A, Uvere E, Hemant T, Balogun O, Adeleye O, Fawale B, Abdulwasiu A, Ogunjimi L, Akinola O, Arulogun O, Donna A, Ogah O, Akinyemi R, Ovbiagele B, Owolabi MO; SIREN. J Neurol Sci. 2021 Aug 15;427:117535. doi: 10.1016/j.jns.2021.117535. Epub 2021 Jun 9. PMID: 34130063; PMCID: PMC8325635.
- Advancing global equity in cancer genomics – challenges and opportunities in Sub-Saharan Africa. Munung NS, Ambele MA, Moela P. Curr Opin Genet Dev. 2021 Feb;66:20-24. doi: 10.1016/j.gde.2020.11.006. Epub 2020 Dec 26. PMID: 33373832.
- Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa. Sarfo FS, Akpa O, Ovbiagele B, Akpalu A, Wahab K, Komolafe M, Obiako R, Owolabi L, Osaigbovo GO, Jenkins C, Ogbole G, Fakunle A, Tiwari HK, Arulogun O, Arnett DK, Asowata O, Ogah O, Akinyemi RO, Owolabi MO; SIREN. J Neurol Sci. 2021 Jul 9;428:117573. doi: 10.1016/j.jns.2021.117573. Epub ahead of print. PMID: 34260999.
- A Novel Afrocentric Stroke Risk Assessment Score: Models from the Siren Study. Akpa O, Sarfo FS, Owolabi M, Akpalu A, Wahab K, Obiako R, Komolafe M, Owolabi L, Osaigbovo GO, Ogbole G, Tiwari HK, Jenkins C, Fakunle AG, Olowookere S, Uvere EO, Akinyemi J, Arulogun O, Akpalu J, Tito-Ilori MM, Asowata OJ, Ibinaiye P, Akisanya C, Oyinloye OI, Appiah L, Sunmonu T, Olowoyo P, Agunloye AM, Adeoye AM, Yaria J, Lackland DT, Arnett D, Laryea RY, Adigun TO, Okekunle AP, Calys-Tagoe B, Ogah OS, Ogunronbi M, Obiabo OY, Isah SY, Dambatta HA, Tagge R, Ogenyi O, Fawale B, Melikam CL, Onasanya A, Adeniyi S, Akinyemi R, Ovbiagele B; SIREN. J Stroke Cerebrovasc Dis. 2021 Jul 28;30(10):106003. doi: 10.1016/j.jstrokecerebrovasdis.2021.106003. Epub ahead of print. PMID: 34332227.
- Genomes arising. Pennisi E. Science. 2021 Feb 5;371(6529):556-559. doi: 10.1126/science.371.6529.556. PMID: 33542121.
- Including Digital Sequence Data in the Nagoya Protocol Can Promote Data Sharing. Ambler J, Diallo AA, Dearden PK, Wilcox P, Hudson M, Tiffin N. Trends Biotechnol. 2021 Feb;39(2):116-125. doi: 10.1016/j.tibtech.2020.06.009. Epub 2020 Jul 10. PMID: 32654776.
- A scoping review of genetics and genomics research ethics policies and guidelines for Africa. Ali J, Cohn B, Mwaka E, Bollinger JM, Kwagala B, Barugahare J, Sewankambo NK, Ochieng J. BMC Med Ethics. 2021 Apr 2;22(1):39. doi: 10.1186/s12910-021-00611-9. PMID: 33810790; PMCID: PMC8017870.
- Stakeholder perspectives on the ethico-legal dimensions of biobanking in South Africa. Singh S, Moodley K. BMC Med Ethics. 2021 Jul 1;22(1):84. doi: 10.1186/s12910-021-00645-z. PMID: 34210291; PMCID: PMC8247071.
- The Genetics of Human Schistosomiasis Infection Intensity and Liver Disease: A Review. Mewamba EM, Nyangiri OA, Noyes HA, Egesa M, Matovu E, Simo G. Front Immunol. 2021 Feb 15;12:613468. doi: 10.3389/fimmu.2021.613468. PMID: 33659002; PMCID: PMC7917240.
- Friedreich ataxia in a family from Mali, West Africa/Friedreich ataxia in a Malian family. Cissé CAK, Cissé L, Ba HO, Samassékou O, Simaga A, Taméga A, Diarra S, Diallo SH, Coulibaly T, Diallo S, Yalcouyé A, Maiga AB, Keita M, Fischbeck KH, Traoré SF, Guinto CO, Landouré G; from the H3Africa Consortium. Clin Case Rep. 2021 Mar 24;9(5):e04065. doi: 10.1002/ccr3.4065. PMID: 34084490; PMCID: PMC8142306.
- Ten-year risk of fatal cardiovascular disease and its association with metabolic risk factors among waste pickers in South Africa. Made F, Nonterah EA, Tlotleng N, Ntlebi V, Naicker N. BMC Cardiovasc Disord. 2021 Jul 10;21(1):336. doi: 10.1186/s12872-021-02150-y. PMID: 34246223; PMCID: PMC8272349.
- From Ebola to COVID-19: emergency preparedness and response plans and actions in Lagos, Nigeria. Abayomi A, Balogun MR, Bankole M, Banke-Thomas A, Mutiu B, Olawepo J, Senjobi M, Odukoya O, Aladetuyi L, Ejekam C, Folarin A, Emmanuel M, Amodu F, Ologun A, Olusanya A, Bakare M, Alabi A, Abdus-Salam I, Erinosho E, Bowale A, Omilabu S, Saka B, Osibogun A, Wright O, Idris J, Ogunsola F. Global Health. 2021 Jul 9;17(1):79. doi: 10.1186/s12992-021-00728-x. PMID: 34243790; PMCID: PMC8267235.
- Should Feedback of Individual Results be Integrated into the Consent Process in African Genomics? Participants’ Views from an HIV-TB Genomics Research Project in Botswana. Ralefala D, Kasule M, Wonkam A, Matshaba M, de Vries J. AJOB Empir Bioeth. 2021 Jul 1:1-9. doi: 10.1080/23294515.2021.1941414. Epub ahead of print. PMID: 34197280.
- The Genetics of Human Schistosomiasis Infection Intensity and Liver Disease: A Review. Mewamba EM, Nyangiri OA, Noyes HA, Egesa M, Matovu E, Simo G. Front Immunol. 2021 Feb 15;12:613468. doi: 10.3389/fimmu.2021.613468. PMID: 33659002; PMCID: PMC7917240.
- Mapping experiences and perspectives of equity in international health collaborations: a scoping review. Faure MC, Munung NS, Ntusi NAB, Pratt B, de Vries J. Int J Equity Health. 2021 Jan 9;20(1):28. doi: 10.1186/s12939-020-01350-w. PMID: 33422065; PMCID: PMC7796532.
- Metabolic Traits and Stroke Risk in Individuals of African Ancestry: Mendelian Randomization Analysis. Fatumo S, Karhunen V, Chikowore T, Sounkou T, Udosen B, Ezenwa C, Nakabuye M, Soremekun O, Daghlas I, Ryan DK, Taylor A, Mason AM, Damrauer SM, Vujkovic M, Keene KL, Fornage M, Järvelin MR, Burgess S, Gill D. Stroke. 2021 Aug;52(8):2680-2684. doi: 10.1161/STROKEAHA.121.034747. Epub 2021 Jun 3. PMID: 34078102; PMCID: PMC8312569.
- Genetic diversity and population structure of Plasmodium falciparum in Nigeria: insights from microsatellite loci analysis. Ajogbasile FV, Kayode AT, Oluniyi PE, Akano KO, Uwanibe JN, Adegboyega BB, Philip C, John OG, Eromon PJ, Emechebe G, Finimo F, Ogbulafor N, Jiya N, Okafor U, Ambe J, Wammanda RD, Oguche S, Mokuolu OA, Sowunmi A, Folarin OA, Happi CT. Malar J. 2021 May 26;20(1):236. doi: 10.1186/s12936-021-03734-x. PMID: 34039364; PMCID: PMC8152046.
- Explanatory models for the cause of Fragile X Syndrome in rural Cameroon. Kengne Kamga K, De Vries J, Nguefack S, Munung NS, Wonkam A. J Genet Couns. 2021 Jun 17. doi: 10.1002/jgc4.1440. Epub ahead of print. PMID: 34145661.
- Simulation of African and non-African low and high coverage whole genome sequence data to assess variant calling approaches. Alosaimi S, van Biljon N, Awany D, Thami PK, Defo J, Mugo JW, Bope CD, Mazandu GK, Mulder NJ, Chimusa ER. Brief Bioinform. 2021 Jul 20;22(4):bbaa366. doi: 10.1093/bib/bbaa366. PMID: 33341897; PMCID: PMC8294538.
- Sequence three million genomes across Africa. Wonkam A. Nature. 2021 Feb;590(7845):209-211. doi: 10.1038/d41586-021-00313-7. PMID: 33568829.
- IHP-PING-generating integrated human protein-protein interaction networks on-the-fly. Mazandu GK, Hooper C, Opap K, Makinde F, Nembaware V, Thomford NE, Chimusa ER, Wonkam A, Mulder NJ. Brief Bioinform. 2021 Jul 20;22(4):bbaa277. doi: 10.1093/bib/bbaa277. PMID: 33129201; PMCID: PMC8293832.
- Challenges and Considerations for Delivering Bioinformatics Training in LMICs: Perspectives From Pan-African and Latin American Bioinformatics Networks. V. Ras, P. Carvajal-López, P. Gopalasingam, A. Matimba, P. A. Chauke, N. Mulder, et al. Frontiers in Education 2021 Vol. 6 Issue 278 DOI: 10.3389/feduc.2021.710971 https://www.frontiersin.org/article/10.3389/feduc.2021.710971
- African Global Representation in Biomedical Sciences. Mulder, N., Zass, L., Hamdi, Y., Othman, H., Panji, S., Allali, I., Fakim, Y.J., 2021. Annual Review of Biomedical Data Science 4, 57–81.. doi:10.1146/annurev-biodatasci-102920-112550
- Eyes of Africa: The Genetics of Blindness: Study Design and Methodology. Olawoye O, Chuka-Okosa C, Akpa O, Realini T, Hauser M, Ashaye A. BMC Ophthalmol. 2021 Jul 9;21(1):272. doi: 10.1186/s12886-021-02029-8. PMID: 34243759; PMCID: PMC8267233.
- Has translational genomics come of age in Africa? Kamp, M., et al. (2021). Human Molecular Genetics.
- G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19. Da Rocha, J.E.B., Othman, H., Tiemessen, C.T., Botha, G., Ramsay, M., Masimirembwa, C., Adebamowo, C., Choudhury, A., Brandenburg, J.-T., Matshaba, M., Simo, G., Gamo, F.-J., Hazelhurst, S., Da Rocha, J.E.B., 2021. The Pharmacogenomics Journal.. doi:10.1038/s41397-021-00242-8
- Negotiating political power and stigma around fragile X Syndrome in a rural village in Cameroon: A tale of a royal family and a community. Kengne Kamga K, Munung NS, Nguefack S, Wonkam A, De Vries J. Mol Genet Genomic Med. 2021 Mar;9(3):e1615. doi: 10.1002/mgg3.1615. Epub 2021 Feb 5. PMID: 33544459; PMCID: PMC8104168.
- Simulation of African and non-African low and high coverage whole genome sequence data to assess variant calling approaches. Alosaimi S, van Biljon N, Awany D, Thami PK, Defo J, Mugo JW, Bope CD, Mazandu GK, Mulder NJ, Chimusa ER. Brief Bioinform. 2021 Jul 20;22(4):bbaa366. doi: 10.1093/bib/bbaa366. PMID: 33341897; PMCID: PMC8294538.
- Plant genomics in Africa: present and prospects. Ghazal H, Adam Y, Idrissi Azami A, Sehli S, Nyarko HN, Chaouni B, Olasehinde G, Isewon I, Adebiyi M, Ajani O, Matovu E, Obembe O, Ajamma Y, Kuzamunu G, Pandam Salifu S, Kayondo J, Benkahla A, Adebiyi E. Plant J. 2021 Apr 10. doi: 10.1111/tpj.15272. Epub ahead of print. PMID: 33837593.
- The role of causal knowledge in stigma considerations in African genomics research: Views of South African Xhosa people. Matshabane OP, Campbell MM, Faure MC, Appelbaum PS, Marshall PA, Stein DJ, de Vries J. Soc Sci Med. 2021 May;277:113902. doi: 10.1016/j.socscimed.2021.113902. Epub 2021 Apr 7. PMID: 33865094.
- Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection. Esoh KK, Apinjoh TO, Nyanjom SG, Wonkam A, Chimusa ER, Amenga-Etego L, Amambua-Ngwa A, Achidi EA. Sci Rep. 2021 Jan 13;11(1):1039. doi: 10.1038/s41598-020-79124-1. PMID: 33441574; PMCID: PMC7807043.
- Associations of Emotional, Physical, or Sexual Intimate Partner Violence and Depression Symptoms Among South African Women in a Prospective Cohort Study. Okafor CN, Barnett W, Zar HJ, Nhapi R, Koen N, Shoptaw S, Stein DJ. J Interpers Violence. 2021 May;36(9-10):NP5060-NP5083. doi: 10.1177/0886260518796522. Epub 2018 Aug 30. PMID: 30160637; PMCID: PMC6486451.
- Friedreich ataxia in a family from Mali, West Africa/Friedreich ataxia in a Malian family. Cissé, C.A.K., Cissé, L., Ba, H.O., Samassékou, O., Simaga, A., Taméga, A., Diarra, S., Diallo, S.H., Coulibaly, T., Diallo, S., Yalcouyé, A., Maiga, A.B., Keita, M., Fischbeck, K.H., Traoré, S.F., Guinto, C.O., Landouré, G., 2021. Clinical Case Reports 9.. doi:10.1002/ccr3.4065
- Candidate gene family-based and case-control studies of susceptibility to high Schistosoma mansoni worm burden in African children: a protocol [version 1; peer review: awaiting peer review]. Nyangiri OA, Edwige SA, Koffi M et al. AAS Open Res 2021,4:36 https://doi.org/10.12688/aasopenres.13203.1)
- Genomic investigation of atypical malaria cases in Kanel, northern Senegal. Sy M, Badiane AS, Deme AB, Gaye A, Ndiaye T, Fall FB, Siddle KJ, Dieye B, Ndiaye YD, Diallo MA, Diongue K, Seck MC, Ndiaye IM, Cissé M, Gueye AB, Sène D, Dieye Y, Souané T, MacInnis B, Volkman SK, Wirth DF, Ndiaye D. Malar J. 2021 Feb 19;20(1):103. doi: 10.1186/s12936-021-03637-x. PMID: 33608006; PMCID: PMC7893743.
- The trans-ancestral genomic architecture of glycemic traits. Chen J, Spracklen CN, Marenne G, et al. Nat Genet. 2021 Jun;53(6):840-860. doi: 10.1038/s41588-021-00852-9. Epub 2021 May 31. PMID: 34059833; PMCID: PMC7610958.
- Genomic investigation of a dengue virus outbreak in Thiès, Senegal, in 2018. Gaye A, Ndiaye T, Sy M, Deme AB, Thiaw AB, Sene A, Ndiaye C, Diedhiou Y, Mbaye AM, Ndiaye I, Tomkins-Tinch C, Gomis JF, Badiane AS, MacInnis B, Park DJ, Ndiaye M, Sy N, Sabeti PC, Siddle KJ, Ndiaye D. Sci Rep. 2021 May 14;11(1):10321. doi: 10.1038/s41598-021-89070-1. PMID: 33990632; PMCID: PMC8121849.
- A Longitudinal Study of the Epidemiology of Seasonal Coronaviruses in an African Birth Cohort. Nicol MP, MacGinty R, Workman L, Stadler JAM, Myer L, Allen V, Ah Tow Edries L, Zar HJ. J Pediatric Infect Dis Soc. 2021 May 28;10(5):607-614. doi: 10.1093/jpids/piaa168. PMID: 33528016; PMCID: PMC7928775.
- Prevalence and socio-demographic correlates of tobacco and alcohol use in four sub-Saharan African countries: a cross-sectional study of middle-aged adults. Boua PR, Soo CC, Debpuur C, Maposa I, Nkoana S, Mohamed SF, Choma S, Oduro A, Asiki G, Micklesfield LK, Gómez-Olivé FX, Sorgho H, Mall S, Ramsay M; as members of AWI-Gen and the H3Africa Consortium. BMC Public Health. 2021 Jun 12;21(1):1126. doi: 10.1186/s12889-021-11084-1. PMID: 34118914; PMCID: PMC8196437.
- Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection. Esoh KK, Apinjoh TO, Nyanjom SG, Wonkam A, Chimusa ER, Amenga-Etego L, Amambua-Ngwa A, Achidi EA. Sci Rep. 2021 Jan 13;11(1):1039. doi: 10.1038/s41598-020-79124-1. PMID: 33441574; PMCID: PMC7807043.
- Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study. Machipisa T, Chong M, Muhamed B, Chishala C, Shaboodien G, Pandie S, de Vries J, Laing N, Joachim A, Daniels R, Ntsekhe M, Hugo-Hamman CT, Gitura B, Ogendo S, Lwabi P, Okello E, Damasceno A, Novela C, Mocumbi AO, Madeira G, Musuku J, Mtaja A, ElSayed A, Elhassan HHM, Bode-Thomas F, Okeahialam BN, Zühlke LJ, Mulder N, Ramesar R, Lesosky M, Parks T, Cordell HJ, Keavney B, Engel ME, Paré G. JAMA Cardiol. 2021 Jun 9:e211627. doi: 10.1001/jamacardio.2021.1627. Epub ahead of print. PMID: 34106200; PMCID: PMC8190704.
- African genetic diversity and adaptation inform a precision medicine agenda. Pereira L, Mutesa L, Tindana P, Ramsay M. Nat Rev Genet. 2021 May;22(5):284-306. doi: 10.1038/s41576-020-00306-8. Epub 2021 Jan 11. PMID: 33432191.
- Affordable method for quality DNA for genomic research in low to middle-income country research settings. Onyemata EJ, Jonathan E, Balogun O, Agala N, Ozumba PJ, Croxton T, Nadoma S, Anazodo T, Peters S, Beiswanger CM, Abimiku A. Anal Biochem. 2021 Feb 1;614:114023. doi: 10.1016/j.ab.2020.114023. Epub 2020 Nov 27. PMID: 33249001.
- Bantu-speaker migration and admixture in southern Africa. Choudhury A, Sengupta D, Ramsay M, Schlebusch C. Hum Mol Genet. 2021 Apr 26;30(R1):R56-R63. doi: 10.1093/hmg/ddaa274. PMID: 33367711; PMCID: PMC8117461.
- Promoting diversity and inclusion in neuroscience and neuroethics. Matshabane OP. EBioMedicine. 2021 May;67:103359. doi: 10.1016/j.ebiom.2021.103359. Epub 2021 May 6. PMID: 33965871; PMCID: PMC8114114.
- Ending a diagnostic odyssey-The first case of Takenouchi-Kosaki syndrome in an African patient. Flynn K, Feben C, Lamola L, Carstens N, Krause A, Lombard Z; for DDD‐Africa as members of the H3Africa Consortium. Clin Case Rep. 2021 Mar 2;9(4):2144-2148. doi: 10.1002/ccr3.3966. PMID: 33936654; PMCID: PMC8077267.
- The benefit sharing vision of H3Africa. Dauda B, Joffe S. Dev World Bioeth. 2018 Jun;18(2):165-170. doi: 10.1111/dewb.12185. Epub 2018 Feb 15. PMID: 29446211.
- Using a multiple-delivery-mode training approach to develop local capacity and infrastructure for advanced bioinformatics in Africa. Ras V, Botha G, Aron S, Lennard K, Allali I, Claassen-Weitz S, Mwaikono KS, Kennedy D, Holmes JR, Rendon G, Panji S, Fields CJ, Mulder N. PLoS Comput Biol. 2021 Feb 25;17(2):e1008640. doi: 10.1371/journal.pcbi.1008640. PMID: 33630830; PMCID: PMC7906323.
- Community engagement and feedback of results in the H3Africa AWI-Gen project: Experiences from the Navrongo Demographic and Health Surveillance site in Northern Ghana. Agongo G, Debpuur C, Amenga-Etego L, Nonterah EA, Kaburise MB, Oduro A, Ramsay M, Tindana P. AAS Open Res. 2021 Mar 19;4:15. doi: 10.12688/aasopenres.13081.1. PMID: 33959702; PMCID: PMC8063542.
- Adiposity Phenotypes and Subclinical Atherosclerosis in Adults from Sub-Saharan Africa: An H3Africa AWI-Gen Study. Nonterah EA, Bots ML, Oduro A, Agongo G, Soo CC, Micklesfield LK, Mashinya F, Boua PR, Mohamed SF, Wade AN, Kyobutungi C, Tinto H, Norris SA, Tollman SM, Ramsay M, Grobbee DE, Klipstein-Grobusch K, Crowther NJ; AWI–Gen and the H3Africa Consortium. Glob Heart. 2021 Mar 19;16(1):19. doi: 10.5334/gh.863. PMID: 33833943; PMCID: PMC7977036.
- Genetic substructure and complex demographic history of South African Bantu speakers. Sengupta D, Choudhury A, Fortes-Lima C, Aron S, Whitelaw G, Bostoen K, Gunnink H, Chousou-Polydouri N, Delius P, Tollman S, Gómez-Olivé FX, Norris S, Mashinya F, Alberts M; AWI-Gen Study; H3Africa Consortium, Hazelhurst S, Schlebusch CM, Ramsay M. Nat Commun. 2021 Apr 7;12(1):2080. doi: 10.1038/s41467-021-22207-y. PMID: 33828095; PMCID: PMC8027885.
- Genomics governance: advancing justice, fairness and equity through the lens of the African communitarian ethic of Ubuntu. Munung NS, de Vries J, Pratt B. Med Health Care Philos. 2021 Apr 2. doi: 10.1007/s11019-021-10012-9. Epub ahead of print. PMID: 33797712.
- A scoping review of genetics and genomics research ethics policies and guidelines for Africa. Ali J, Cohn B, Mwaka E, Bollinger JM, Kwagala B, Barugahare J, Sewankambo NK, Ochieng J. BMC Med Ethics. 2021 Apr 2;22(1):39. doi: 10.1186/s12910-021-00611-9. PMID: 33810790; PMCID: PMC8017870.
- Tracking the emergence of new SARS-CoV-2 variants in South Africa. Happi AN, Ugwu CA, Happi CT. Nat Med. 2021 Mar;27(3):372-373. doi: 10.1038/s41591-021-01265-1. PMID: 33723453.
- H3ABioNet genomic medicine and microbiome data portals hackathon proceedings. Fadlelmola FM, Ghedira K, Hamdi Y, Hanachi M, Radouani F, Allali I, Kiran A, Zass L, Alsayed N, Fassatoui M, Samtal C, Ahmed S, Da Rocha J, Chaqsare S, Sallam RM, Chaouch M, Farahat M, Ssekagiri A, Parker Z, Adil M, Turkson M, Benchaalia A, Benkahla A, Panji S, Kassim S, Souiai O, Mulder N. Database (Oxford). 2021 Apr 17;2021:baab016. doi: 10.1093/database/baab016. PMID: 33864455; PMCID: PMC8052916.
- Human OMICs and Computational Biology Research in Africa: Current Challenges and Prospects. Hamdi Y, Zass L, Othman H, Radouani F, Allali I, Hanachi M, Okeke CJ, Chaouch M, Tendwa MB, Samtal C, Mohamed Sallam R, Alsayed N, Turkson M, Ahmed S, Benkahla A, Romdhane L, Souiai O, Tastan Bishop Ö, Ghedira K, Mohamed Fadlelmola F, Mulder N, Kamal Kassim S. OMICS. 2021 Apr 1. doi: 10.1089/omi.2021.0004. Epub ahead of print. PMID: 33794662.
- Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Fatumo S, Chikowore T, Kalyesubula R, Nsubuga RN, Asiki G, Nashiru O, Seeley J, Crampin AC, Nitsch D, Smeeth L, Kaleebu P, Burgess S, Nyirenda M, Franceschini N, Morris AP, Tomlinson L, Newton R. Hum Mol Genet. 2021 Mar 30:ddab088. doi: 10.1093/hmg/ddab088. Epub ahead of print. PMID: 33783510.
- Unmapped exome reads implicate a role for Anelloviridae in childhood HIV-1 long-term non-progression. Mwesigwa S, Williams L, Retshabile G, Katagirya E, Mboowa G, Mlotshwa B, Kyobe S, Kateete DP, Wampande EM, Wayengera M, Mpoloka SW, Mirembe AN, Kasvosve I, Morapedi K, Kisitu GP, Kekitiinwa AR, Anabwani G, Joloba ML, Matovu E, Mulindwa J, Noyes H, Botha G; Collaborative African Genomics Network (CAfGEN); TrypanoGEN Research Group, Brown CW, Mardon G, Matshaba M, Hanchard NA. NPJ Genom Med. 2021 Mar 19;6(1):24. doi: 10.1038/s41525-021-00185-w. PMID: 33741997.
- The Independent Association of Prestroke Psychiatric Symptoms and Acute Phase Delirium with Poststroke Mortality at One Year in Nigeria. Ojagbemi A, Bello T, Owolabi M, Baiyewu O. J Stroke Cerebrovasc Dis. 2021 Apr;30(4):105622. doi: 10.1016/j.jstrokecerebrovasdis.2021.105622. Epub 2021 Jan 23. PMID: 33497933.
- Multimorbidity from Chronic Conditions among Adults in Urban Slums: The AWI-Gen Nairobi Site Study Findings. Mohamed SF, Haregu TN, Uthman OA, Khayeka-Wandabwa C, Muthuri SK, Asiki G, Kyobutungi C, Gill P. Glob Heart. 2021 Jan 20;16(1):6. doi: 10.5334/gh.771. PMID: 33598386; PMCID: PMC7824985.
- Negotiating political power and stigma around fragile X Syndrome in a rural village in Cameroon: A tale of a royal family and a community. Kengne Kamga K, Munung NS, Nguefack S, Wonkam A, De Vries J. Mol Genet Genomic Med. 2021 Feb 5:e1615. doi: 10.1002/mgg3.1615. Epub ahead of print. PMID: 33544459.
- Non-communicable diseases pandemic and precision medicine: Is Africa ready? Chikowore T, Kamiza AB, Oduaran OH, Machipisa T, Fatumo S. EBioMedicine. 2021 Feb 24;65:103260. doi: 10.1016/j.ebiom.2021.103260. Epub ahead of print. PMID: 33639396; PMCID: PMC7921515.
- The impact of psychopathology, social adversity and stress-relevant DNA methylation on prospective risk for post-traumatic stress: A machine learning approach. Wani AH, Aiello AE, Kim GS, Xue F, Martin CL, Ratanatharathorn A, Qu A, Koenen K, Galea S, Wildman DE, Uddin M. J Affect Disord. 2021 Mar 1;282:894-905. doi: 10.1016/j.jad.2020.12.076. Epub 2020 Dec 24. PMID: 33601733; PMCID: PMC7942200.
- Transcription-translation error: In-silico investigation of the structural and functional impact of deleterious single nucleotide polymorphisms in GULP1 gene. Soremekun OS, Ezenwa C, Soliman M, Chikowore T, Nashiru O, Fatumo S. Inform Med Unlocked. 2021;22:100503. doi: 10.1016/j.imu.2020.100503. Epub 2020 Dec 24. PMID: 33665355; PMCID: PMC7928429.
- Affordable method for quality DNA for genomic research in low to middle-income country research settings.
Onyemata EJ, Jonathan E, Balogun O, Agala N, Ozumba PJ, Croxton T, Nadoma S, Anazodo T, Peters S, Beiswanger CM, Abimiku A. Anal Biochem. 2021 Feb 1;614:114023. doi: 10.1016/j.ab.2020.114023. Epub 2020 Nov 27. PMID: 33249001. - Conceptual framework for establishing the African Stroke Organization. Akinyemi R, Sarfo F, Abd-Allah F, Ogun Y, Belo M, Francis P, Mateus MB, Bateman K, Naidoo P, Charway-Felli A, Akpalu A, Wahab K, Napon C, Arulogun O, Ebenezer AA, Ekeng G, Scola G, Hamzat K, Zimba S, Ossou-Nguiet PM, Ademokoya J, Adebayo P, Ayele BA, Vaz DC, Ogbole G, Barasukan P, Melifonwu R, Onwuekwe I, Belson S, Damasceno A, Okubadejo N, Njamnshi AK, Ogeng’o J, Walker RW, Diop AG, Ogunniyi A, Kalaria R, Sandercock P, Davis S, Brainin M, Ovbiagele B, Owolabi M. Int J Stroke. 2021 Jan;16(1):93-99. doi: 10.1177/1747493019897871. Epub 2020 Feb 6. PMID: 32026763.
- Factors associated with hypertension among stroke-free indigenous Africans: Findings from the SIREN study. Akpa OM, Okekunle AP, Ovbiagele B, Sarfo FS, Akinyemi RO, Akpalu A, Wahab KW, Komolafe M, Obiako R, Owolabi LF, Ogbole G, Fawale B, Fakunle A, Asaleye CM, Akisanya CO, Hamisu DA, Ogunjimi L, Adeoye A, Ogah O, Lackland D, Uvere EO, Faniyan MM, Asowata OJ, Adeleye O, Aridegbe M, Olunuga T, Yahaya IS, Olaleye A, Calys-Tagoe B, Owolabi MO; SIREN Study as part of the H3Africa Consortium. J Clin Hypertens (Greenwich). 2021 Jan 23. doi: 10.1111/jch.14183. Epub ahead of print. PMID: 33484599.
- Targeting Fc effector function in vaccine design. Richardson SI, Moore PL. Expert Opin Ther Targets. 2021 Jun;25(6):467-477. doi: 10.1080/14728222.2021.1907343. Epub 2021 Apr 6. PMID: 33754933.
- Poor cardiovascular health is associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations: an H3Africa AWI-Gen study. Nonterah EA, Crowther NJ, Oduro A, Agongo G, Micklesfield LK, Boua PR, Choma SSR, Mohamed SF, Sorgho H, Tollman SM, Norris SA, Raal FJ, Grobbee DE, Ramsay M, Bots ML, Klipstein-Grobusch K; as part of the H3Africa AWI-Gen study. BMC Med. 2021 Feb 10;19(1):30. doi: 10.1186/s12916-021-01909-6. PMID: 33563289; PMCID: PMC7874493.
- Overview of The Human Heredity and Health in Africa Kidney Disease Research Network (H3A-KDRN). Dwomoa Adu, Akinlolu Ojo and the H3A-KDRN Investigators Kidney360 January 2021, 2 (1) 129-133; DOI: https://doi.org/10.34067/KID.0002592020.
- A pooled testing strategy for identifying SARS-CoV-2 at low prevalence. Mutesa L, Ndishimye P, Butera Y, Souopgui J, Uwineza A, Rutayisire R, Ndoricimpaye EL, Musoni E, Rujeni N, Nyatanyi T, Ntagwabira E, Semakula M, Musanabaganwa C, Nyamwasa D, Ndashimye M, Ujeneza E, Mwikarago IE, Muvunyi CM, Mazarati JB, Nsanzimana S, Turok N, Ndifon W. Nature. 2021 Jan;589(7841):276-280. doi: 10.1038/s41586-020-2885-5. Epub 2020 Oct 21. PMID: 33086375.
- Short Communication: Genetic Variation in Human IL10 Proximal Promoter and Susceptibility to HIV-1 Infection in Mali, West Africa. Dabitao D, Dembele M, Urbanowski M, Kone B, Wague M, Coulibaly N, Sarro YDS, Baya B, Goita D, Dao S, Belson M, Klein SL, Achenbach C, Holl JL, Diakite M, Doumbia S, Bream JH, Bishai WR, Diallo S, Murphy RL. AIDS Res Hum Retroviruses. 2021 Jan;37(1):57-61. doi: 10.1089/AID.2020.0140. Epub 2020 Nov 23. PMID: 33045845.
- Toward better governance of human genomic data. O’Doherty KC, Shabani M, Dove ES, Bentzen HB, Borry P, Burgess MM, Chalmers D, De Vries J, Eckstein L, Fullerton SM, Juengst E, Kato K, Kaye J, Knoppers BM, Koenig BA, Manson SM, McGrail KM, McGuire AL, Meslin EM, Nicol D, Prainsack B, Terry SF, Thorogood A, Burke W. Nat Genet. 2021 Jan;53(1):2-8. doi: 10.1038/s41588-020-00742-6. PMID: 33414545.
- Integrated molecular characterisation of the MAPK pathways in human cancers reveals pharmacologically vulnerable mutations and gene dependencies. Sinkala M, Nkhoma P, Mulder N, Martin DP. Commun Biol. 2021 Jan 4;4(1):9. doi: 10.1038/s42003-020-01552-6. PMID: 33398072; PMCID: PMC7782843.
- Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection. Esoh KK, Apinjoh TO, Nyanjom SG, Wonkam A, Chimusa ER, Amenga-Etego L, Amambua-Ngwa A, Achidi EA.Sci Rep. 2021 Jan 13;11(1):1039. doi: 10.1038/s41598-020-79124-1. PMID: 33441574; PMCID: PMC7807043.
- Polymorphisms in Plasmodium falciparum dihydropteroate synthetase and dihydrofolate reductase genes in Nigerian children with uncomplicated malaria using high-resolution melting technique. Kayode AT, Ajogbasile FV, Akano K, Uwanibe JN, Oluniyi PE, Eromon PJ, Folarin OA, Sowunmi A, Wirth DF, Happi CT. Sci Rep. 2021 Jan 12;11(1):471. doi: 10.1038/s41598-020-80017-6. PMID: 33436791; PMCID: PMC7803958.
- Polymorphisms in Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and multidrug-resistant gene 1 (Pfmdr-1) in Nigerian children 10 years post-adoption of artemisinin-based combination treatments. Kayode AT, Akano K, Ajogbasile FV, Uwanibe JN, Oluniyi PE, Bankole BE, Eromon PJ, Sowunmi A, Folarin OA, Volkman SK, McInnis B, Sabeti P, Wirth DF, Happi CT. Int J Parasitol. 2021 Mar;51(4):301-310. doi: 10.1016/j.ijpara.2020.10.001. Epub 2020 Dec 24. PMID: 33359205; PMCID: PMC7940560.
- Genomics and bioinformatics capacity in Africa: no continent is left behind. Mboowa G, Sserwadda I, Aruhomukama D. Genome. 2021 Jan 12:1-11. doi: 10.1139/gen-2020-0013. Epub ahead of print. PMID: 33433259.