Biobanking in a Challenging African Environment: Unique Experience from the SIREN Project. Akinyemi RO, Akinwande K, Diala S, Adeleye O, Ajose A, Issa K, Owusu D, Boamah I, Yahaya IS, Jimoh AO, Imoh L, Fakunle G, Akpalu A, Sarfo F, Wahab K, Sanya E, Owolabi L, Obiako R, Osaigbovo G, Komolafe M, Fawale M, Adebayo P, Olowoyo P, Obiabo Y, Sunmonu T, Chukwuonye I, Balogun O, Adeoye B, Oladele F, Olowoniyi P, Adeyemi F, Lezzi A, Falayi AT, Fasanya M, Ogunwale K, Adeola O, Olomu O, Aridegbe O, Laryea R, Uvere E, Faniyan M, Melikam E, Tagge R, Akpa O, Akinyemi J, Arulogun O, Tiwari HK, Ovbiagele B, Owolabi MO. Biopreserv Biobank. 2018 Jun;16(3):217-232. doi: 10.1089/bio.2017.0113. Epub 2018 May 7. PMID: 29733683; PMCID: PMC5995267.
Genomic and environmental risk factors for cardiometabolic diseases in Africa: methods used for Phase 1 of the AWI-Gen population cross-sectional study. Ali SA, Soo C, Agongo G, Alberts M, Amenga-Etego L, Boua RP, Choudhury A, Crowther NJ, Depuur C, Gómez-Olivé FX, Guiraud I, Haregu TN, Hazelhurst S, Kahn K, Khayeka-Wandabwa C, Kyobutungi C, Lombard Z, Mashinya F, Micklesfield L, Mohamed SF, Mukomana F, Nakanabo-Diallo S, Natama HM, Ngomi N, Nonterah EA, Norris SA, Oduro AR, Somé AM, Sorgho H, Tindana P, Tinto H, Tollman S, Twine R, Wade A, Sankoh O, Ramsay M. Glob Health Action. 2018;11(sup2):1507133. doi: 10.1080/16549716.2018.1507133. PMID: 30259792; PMCID: PMC6161608.
Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018. Siddle KJ, Eromon P, Barnes KG, Mehta S, Oguzie JU, Odia I, Schaffner SF, Winnicki SM, Shah RR, Qu J, Wohl S, Brehio P, Iruolagbe C, Aiyepada J, Uyigue E, Akhilomen P, Okonofua G, Ye S, Kayode T, Ajogbasile F, Uwanibe J, Gaye A, Momoh M, Chak B, Kotliar D, Carter A, Gladden-Young A, Freije CA, Omoregie O, Osiemi B, Muoebonam EB, Airende M, Enigbe R, Ebo B, Nosamiefan I, Oluniyi P, Nekoui M, Ogbaini-Emovon E, Garry RF, Andersen KG, Park DJ, Yozwiak NL, Akpede G, Ihekweazu C, Tomori O, Okogbenin S, Folarin OA, Okokhere PO, MacInnis BL, Sabeti PC, Happi CT. N Engl J Med. 2018 Nov 1;379(18):1745-1753. doi: 10.1056/NEJMoa1804498. Epub 2018 Oct 17. PMID: 30332564; PMCID: PMC6181183.
Whole-Exome Sequencing Reveals Uncaptured Variation and Distinct Ancestry in the Southern African Population of Botswana. Retshabile G, Mlotshwa BC, Williams L, Mwesigwa S, Mboowa G, Huang Z, Rustagi N, Swaminathan S, Katagirya E, Kyobe S, Wayengera M, Kisitu GP, Kateete DP, Wampande EM, Maplanka K, Kasvosve I, Pettitt ED, Matshaba M, Nsangi B, Marape M, Tsimako-Johnstone M, Brown CW, Yu F, Kekitiinwa A, Joloba M, Mpoloka SW, Mardon G, Anabwani G, Hanchard NA; Collaborative African Genomics Network (CAfGEN) of the H3Africa Consortium. Am J Hum Genet. 2018 May 3;102(5):731-743. doi: 10.1016/j.ajhg.2018.03.010. Epub 2018 Apr 26. PMID: 29706352; PMCID: PMC5986695.
Dating admixture events is unsolved problem in multi-way admixed populations. Chimusa ER, Defo J, Thami PK, Awany D, Mulisa DD, Allali I, Ghazal H, Moussa A, Mazandu GK. Brief Bioinform. 2018 Nov 19. doi: 10.1093/bib/bby112. Epub ahead of print. Erratum in: Brief Bioinform. 2020 Mar 23;21(2):751. PMID: 30462157.
Gaps in Guidelines for the Management of Diabetes in Low- and Middle-Income Versus High-Income Countries-A Systematic Review. Owolabi MO, Yaria JO, Daivadanam M, Makanjuola AI, Parker G, Oldenburg B, Vedanthan R, Norris S, Oguntoye AR, Osundina MA, Herasme O, Lakoh S, Ogunjimi LO, Abraham SE, Olowoyo P, Jenkins C, Feng W, Bayona H, Mohan S, Joshi R, Webster R, Kengne AP, Trofor A, Lotrean LM, Praveen D, Zafra-Tanaka JH, Lazo-Porras M, Bobrow K, Riddell MA, Makrilakis K, Manios Y, Ovbiagele B; COUNCIL Initiative. Diabetes Care. 2018 May;41(5):1097-1105. doi: 10.2337/dc17-1795. PMID: 29678866; PMCID: PMC5911785.
Knowledge, attitudes and practices of West Africans on genetic studies of stroke: Evidence from the SIREN Study. Akinyemi RO, Sarfo FS, Akinyemi J, Singh A, Onoja Akpa M, Akpalu A, Owolabi L, Adeoye AM, Obiako R, Wahab K, Sanya E, Komolafe M, Ogbole G, Fawale M, Adebayo P, Osaigbovo G, Sunmonu T, Olowoyo P, Chukwuonye I, Obiabo Y, Adeniji O, Fakunle G, Melikam E, Saulson R, Yaria J, Uwanruochi K, Ibinaiye P, Amusa GA, Yahaya IS, Dambatta AH, Faniyan M, Olowoniyi P, Bock-Oruma A, Joseph OC, Oguntade A, Kolo P, Laryea R, Lakoh S, Uvere E, Farombi T, Akpalu J, Oyinloye O, Appiah L, Calys-Tagoe B, Shidali V, Tabari NA, Adebayo O, Efidi R, Adeleye O, Owusu D, Ogunjimi L, Aridegbe O, Imoh CL, Sanni T, Gebreziabher M, Hemant T, Arulogun O, Ogunniyi A, Jenkins C, Owolabi M, Ovbiagele B. Int J Stroke. 2019 Jan;14(1):69-79. doi: 10.1177/1747493018790059. Epub 2018 Jul 24. PMID: 30040054; PMCID: PMC8325169.
Including all voices in international data-sharing governance. Kaye J, Terry SF, Juengst E, Coy S, Harris JR, Chalmers D, Dove ES, Budin-Ljøsne I, Adebamowo C, Ogbe E, Bezuidenhout L, Morrison M, Minion JT, Murtagh MJ, Minari J, Teare H, Isasi R, Kato K, Rial-Sebbag E, Marshall P, Koenig B, Cambon-Thomsen A. Hum Genomics. 2018 Mar 7;12(1):13. doi: 10.1186/s40246-018-0143-9. PMID: 29514717; PMCID: PMC5842530.
Hackathons as a means of accelerating scientific discoveries and knowledge transfer. Ghouila A, Siwo GH, Entfellner JD, Panji S, Button-Simons KA, Davis SZ, Fadlelmola FM; DREAM of Malaria Hackathon Participants, Ferdig MT, Mulder N. Genome Res. 2018 May;28(5):759-765. doi: 10.1101/gr.228460.117. Epub 2018 Apr 12. PMID: 29650552; PMCID: PMC5932615.
Regional and sex-specific variation in BMI distribution in four sub-Saharan African countries: The H3Africa AWI-Gen study. Ramsay M, Crowther NJ, Agongo G, Ali SA, Asiki G, Boua RP, Gómez-Olivé FX, Kahn K, Khayeka-Wandabwa C, Mashinya F, Micklesfield L, Mukomana F, Nonterah EA, Soo C, Sorgho H, Wade AN, Wagner RG, Alberts M, Hazelhurst S, Kyobutungi C, Norris SA, Oduro AR, Sankoh O, Tinto H, Tollman S; as members of AWI-Gen and the H3Africa Consortium. Glob Health Action. 2018;11(sup2):1556561. doi: 10.1080/16549716.2018.1556561. PMID: 30845902; PMCID: PMC6407581.
Developing reproducible bioinformatics analysis workflows for heterogeneous computing environments to support African genomics. Baichoo S, Souilmi Y, Panji S, Botha G, Meintjes A, Hazelhurst S, Bendou H, Beste E, Mpangase PT, Souiai O, Alghali M, Yi L, O’Connor BD, Crusoe M, Armstrong D, Aron S, Joubert F, Ahmed AE, Mbiyavanga M, Heusden PV, Magosi LE, Zermeno J, Mainzer LS, Fadlelmola FM, Jongeneel CV, Mulder N. BMC Bioinformatics. 2018 Nov 29;19(1):457. doi: 10.1186/s12859-018-2446-1. PMID: 30486782; PMCID: PMC6264621.
Organizing and running bioinformatics hackathons within Africa: The H3ABioNet cloud computing experience. Ahmed AE, Mpangase PT, Panji S, Baichoo S, Souilmi Y, Fadlelmola FM, Alghali M, Aron S, Bendou H, De Beste E, Mbiyavanga M, Souiai O, Yi L, Zermeno J, Armstrong D, O’Connor BD, Mainzer LS, Crusoe MR, Meintjes A, Van Heusden P, Botha G, Joubert F, Jongeneel CV, Hazelhurst S, Mulder N. AAS Open Res. 2019 Aug 7;1:9. doi: 10.12688/aasopenres.12847.2. PMID: 32382696; PMCID: PMC7194140.
The benefit sharing vision of H3Africa. Dauda B, Joffe S. Dev World Bioeth. 2018 Jun;18(2):165-170. doi: 10.1111/dewb.12185. Epub 2018 Feb 15. PMID: 29446211.
Renewing Felsenstein’s phylogenetic bootstrap in the era of big data. Lemoine F, Domelevo Entfellner JB, Wilkinson E, Correia D, Dávila Felipe M, De Oliveira T, Gascuel O. 2018 Apr;556(7702):452-456. doi: 10.1038/s41586-018-0043-0. Epub 2018 Apr 18. PMID: 29670290 PMCID: PMC6030568 DOI: 10.1038/s41586-018-0043-0 Free PMC article
Including all voices in international data-sharing governance. Kaye J, Terry SF, Juengst E, Coy S, Harris JR, Chalmers D, Dove ES, Budin-Ljøsne I, Adebamowo C, Ogbe E, Bezuidenhout L, Morrison M, Minion JT, Murtagh MJ, Minari J, Teare H, Isasi R, Kato K, Rial-Sebbag E, Marshall P, Koenig B, Cambon-Thomsen A. 2018 Mar 7;12(1):13. doi: 10.1186/s40246-018-0143-9. PMID: 29514717 PMCID: PMC5842530 DOI: 10.1186/s40246-018-0143-9 Free PMC article
Dominant modifiable risk factors for stroke in Ghana and Nigeria (SIREN): a case-control study. Owolabi MO, Sarfo F, Akinyemi R, Gebregziabher M, Akpa O, Akpalu A, Wahab K, Obiako R, Owolabi L, Ovbiagele B; SIREN Team.; as part of H3Africa Consortium. 2018 Apr;6(4):e436-e446. doi: 10.1016/S2214-109X(18)30002-0. Epub 2018 Feb 26. PMID: 29496511 PMCID: PMC5906101 DOI: 10.1016/S2214-109X(18)30002-0 Free PMC article
Implementation of genomics research in Africa: challenges and recommendations. Sally N Adebamowo, Veronica Francis, Ernest Tambo, Seybou H Diallo, Guida Landouré, Victoria Nembaware, Eileen Dareng, Babu Muhamed, Michael Odutola, Teniola Akeredolu, Barbara Nerima, Petronilla J Ozumba, Slee Mbhele, Anita Ghanash, Ablo P Wachinou, Nicholas Ngomi. 2018;11(1):1419033. doi: 10.1080/16549716.2017.1419033. PMID: 29336236 PMCID: PMC5769805 DOI: 10.1080/16549716.2017.1419033 Free PMC article
The epidemiology of stroke in Africa: A systematic review of existing methods and new approaches. Mayowa Owolabi, Paul Olowoyo, Femi Popoola, Daniel Lackland, Carolyn Jenkins, Oyedunni Arulogun, Rufus Akinyemi, Odunayo Akinyemi, Onoja Akpa, Olanrewaju Olaniyan, Ezinne Uvere, Issa Kehinde, Anbesaw Selassie, Mulugeta Gebregziabher, Raelle Tagge, Bruce Ovbiagele. 2018 Jan;20(1):47-55. doi: 10.1111/jch.13152. PMID: 29228472 PMCID: PMC5777902 DOI: 10.1111/jch.13152 Free PMC article
APOL1, CDKN2A/CDKN2B, and HDAC9 polymorphisms and small vessel ischemic stroke. R Akinyemi, H K Tiwari, D K Arnett, B Ovbiagele, M R Irvin, K Wahab, F Sarfo, V Srinivasasainagendra, A Adeoye, R T Perry, A Akpalu, C Jenkins, O Arulogun, M Gebregziabher, L Owolabi, R Obiako, E Sanya, M Komolafe, M Fawale, P Adebayo, G Osaigbovo, T Sunmonu, P Olowoyo, I Chukwuonye, Y Obiabo, A Onoja, J Akinyemi, G Ogbole, S Melikam, R Saulso, M Owolabi, SIREN Investigators. 2018 Jan;137(1):133-141. doi: 10.1111/ane.12847. Epub 2017 Oct 3.PMID: 28975602 PMCID: PMC5716854 DOI: 10.1111/ane.12847 Free PMC article
Hendry, L. M., Sahibdeen, V., Choudhury, A., Norris, S. A., Ramsay, M., & Lombard, Z. (2018). Insights into the genetics of blood pressure in black South African individuals: The birth to twenty cohort.BMC Medical Genomics, 11(1) doi:10.1186/s12920-018-0321-6
Micklesfield, L. K., Kagura, J., Munthali, R., Crowther, N. J., Jaff, N., Gradidge, P., & Ramsay, M. (2018). Demographic, socio-economic and behavioural correlates of BMI in middle-aged black men and women from urban Johannesburg, South Africa. Global Health Action, 11(Suppl 2), 1448250. Doi: 10.1080/16549716.2018.1448250
Ali, S.A., Soo, C., Agongo, G., Alberts, M., Amenga-Etego, L., Boua, P.R., Choudhury, A., Crowther, N.J., and Debpuur, C., et al., (2018) Genomic and environmental risk factors for cardiometabolic diseases in Africa: methods used for Phase 1 of the AWI-Gen population cross-sectional study. Global Health Action, 11(2) 1507133. Doi: 10.1080
Regional and sex-specific variation in BMI distribution in four sub-Saharan African countries: The H3Africa AWI-Gen study. Michèle Ramsay, Nigel J. Crowther, Godfred Agongo, Stuart A. Ali, Gershim Asiki, Romuald P. Boua, F. Xavier Gómez-Olivé, Kathleen Kahn, Christopher Khayeka-Wandabwa, Felistas Mashinya, Lisa Micklesfield, Freedom Mukomana, Engelbert A. Nonterah, Cassandra Soo, Hermann Sorgho, Alisha N. Wade, Ryan G. Wagner, Marianne Alberts, Scott Hazelhurst, Catherine Kyobutungi, Shane A. Norris, Abraham R. Oduro, Osman Sankoh, Halidou Tinto, Stephen Tollman & as members of AWI-Gen and the H3Africa Consortium (2018) 11:sup2, 1556561, DOI: 10.1080/16549716.2018.1556561
H3Africa: An Africa exemplar? Nnamuchi O. Exploring its framework on protecting human research participants. Dev World Bioeth. 2018 Jun;18(2):156-164. doi: 10.1111/dewb.12150. Epub 2017 May 3. PMID: 28470782.
Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa. Akinyemi RO, Owolabi MO, Ihara M, Damasceno A, Ogunniyi A, Dotchin C, Paddick SM, Ogeng’o J, Walker R, Kalaria RN. Brain Res Bull. 2019 Feb;145:97-108. doi: 10.1016/j.brainresbull.2018.05.018. Epub 2018 May 25. PMID: 29807146; PMCID: PMC6252289.