Mental Health Working Group 2020 Minutes

November 1, 2020

2020 Minutes

Mental Health Working Group 2019 Minutes
October 8, 2020

Breast Milk Microbiota Influence on Infant Immunity and Growth (BEAMING)

Understanding microbial shifts and how they affect vaccine response is central to this study. We will determine if gut microbial communities associated with breastfeeding in the HEU infant follows the same successional trajectory as HU controls and resolve the differences at functional level. How the continuous conditioning of the infant gut by the microbiota from the breast milk affects the infant microbiome and subsequent
October 7, 2020

Intergenerational Epigenomics of Trauma and PTSD in Rwanda

The goal of the proposed work is to characterize the transgenerational genomic impact of genocide exposure and post-traumatic stress disorder (PTSD) in women survivors of the Rwandan genocide and their offspring. PTSD is a common and debilitating mental disorder that has a profound public health impact. Between April and June 1994, almost one million people died in the Rwandan genocide against ethnic Tutsi.
October 6, 2020

Transgenerational Effects of Maternal Stressors: Investigating the Role of Infant Gene Expression

This collaborative project, between Emory University in the USA and the University of Cape Town (UCT) in South Africa, proposes to investigate biological mechanisms underlying the transgenerational effects of exposure to prenatal maternal psychological stress, anxiety, or depression. We propose to examine
October 1, 2020

Immunoglobulin Gene Diversity in an African Population and Impact Antibody Function in HIV Infection

Antibodies are critical components of immune defense and are mediators of vaccine-elicited protection as well as autoimmunity. The heavy and light chains that comprise an antibody molecule are encoded by germline immunoglobulin (Ig) gene fragments that recombine and undergo somatic mutation thereby generating billions of specificities able to contend with a multitude of foreign antigens.
October 1, 2020

Nurturing Genomics and Bioinformatics Research Capacity in Africa (BRECA)

Bioinformatics is now integral to clinical and biomedical research. Without bioinformatics expertise, health research in Africa will remain suboptimal. In fact, researchers on the continent are stuck with Next Generation Sequencing data that they can barely analyze.
September 29, 2020

African Neurobiobank for Precision Stroke Medicine: ELSI Project

African Neurobiobank for Precision Stroke Medicine: ELSI Project: Project Summary Africa had, hitherto, been under-represented in the biobanking revolution. However, with the Human, Heredity and Health in Africa (H3Africa) initiative, biorepository science has been bolstered and biobanking related activities are growing on the continent
September 28, 2020

2020 Minutes

September 28, 2020

Ethical and Social issues in Informed Consent Processes in African Genomic Research

Sub Saharan Africa (SSA), which bears 24% of the world’s burden of disease, is also home to: the highest human genetic diversity, vast array of environments, and a diversity of cultural practices. Whereas most of this disease burden has till recently been attributed to various infectious diseases like HIV/AIDS, the onset of the new and concurrent non communicable diseases epidemic is creating unique opportunities