We welcome you to the Sixteenth Meeting of the H3Africa Consortium. As you know we were due to meet in Tanzania this September with the African Society of Human Genetics. Unfortunately we have all been forced into detours which has created opportunities for creative engagement. We hope that our virtual meeting experience will offer as many opportunities to share research findings and build upon them. We will dedicate time to explore research areas beyond the current scope of H3Africa to foster broader sustainable networks. Our early career scientists are always a key feature of H3Africa meetings, there will be several opportunities to engage young scientists during presentation and poster sessions. Our Principal Investigators and Scientists have also responded to the Covid-19 pandemic at various levels and are keen to share their experiences and findings with you. We appreciate your participation during this virtual meeting and look forward to meeting you in-person in time.