Eleventh H3Africa Consortium Meeting
VENUE: Serena Lake Victoria Entebbe Uganda
Wednesday, 21st March 2018 |
| H3Africa Fellow day |
Thursday, 22nd March 2018 |
| Overview & Policy Highlights
Principal Invistigators/Working Groups/Poster Sessions |
Friday, 23rd March 2018 |
| Principal Invistigators/Working
Groups/Sustainability Session |
Saturday, 24th March 2018 |
| Principal Invistigators/Working
Groups & Report Back |
Sunday, 25th March 2018 |
| Excursion to Makerere University |
Gallery
Eleventh H3Africa Consortium Meeting Wednesday 21 March 2018 Serena Lake Victoria Kalangala Hall |
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| 6:00 | Bus departs from Makerere with 47 plus participants | |
| 8:00 – 8:30 | Registration | |
| 8:30-9:00 | Opening & Welcome | |
| Session 1 | Understanding Strains, Lineages, and Population Histories | |
| 9:00-9:10 | Begna Tulu Eticha | Spoligo typing based genetic diversity of Mycobacterium tuberculosis in Ethiopia: Asystematic review |
| 9:10-9:20 | Biniam Wondale | Genetic Diversity of Clinical Mycobacterium Tuberculosis Complex Isolates in South Omo, southern Ethiopia |
| 9:20-9:30 | Rendani Manenzhe | Shotgun Sequencingto Elucidate Pneumococal Strain Level Nasopharyngeal Colonization Patterns and Antimicrobial Resistance in A South African Birth Cohort. |
| 9:30-9:40 | Dhriti Sengupta | Insights on African Demographic History UsingDeep Whole Genome Sequences |
| 9:40-10:00 | Panel Discussion | |
| Session 2 | Facets of Community Engagement in Genomics Research | |
| 10:00–10:10 | Rasheed Taiwo | Qualitative Study of Linguistic and Cultural Concepts o fHeritability in Nigeria |
| 10:10 –10:20 | Gerald Mboowa | Role of Genomic Education in Reducing the burden of Common Genetic Diseases in Africa |
| 10:20-10:30 | Emmanuel Jonathan | Stronger Together: Partnerships between Clinical Sites and Biobanks towards the Common Goal ofHigh Quality Biospecimens |
| 10:30-10:45 | Panel Discussion | |
| 10:45-11:30 | Poster Session & Tea | |
| Session 3 | Informatics Tools for Omics Research | |
| 11:30-11:40 | Mamadou D Coulibaly | Collection of biological data on mobile devices in the epidemiological surveillance of Malaria in Koila Bamanan and Dangassa (Mali): Development of an Android application |
| 11:40-11:50 | Sara El Jadid | |
| 11:50– 12:00 | Panel Discussion | |
| Session 4 | Host/Pathogen and Pathogen/Drug Interactions | |
| 12:00-12:10 | Yasmine Ochi | Characterization of Inter-species Protein Interactions:Use of SLiM motifs to infer interactions between Plasmodium falciparum and its hosts |
| 12:10-12:20 | Haddijiatou Mbye | Increasing ex-vivo tolerance of Gambian Plasmodium falciparum isolates to Artemisinin-based Combination Therapy partner drugs |
| 12:20-12:30 | Wondimu Ashagre Awoke | In vitro starvation model for Assessing Phenotypic Drug Toleranceon MycobacteriumTuberculosis
Ashagre, Kassu Desta, Endalamaw Gadissa. |
| 12:30-12:40 | Panel Discussion | |
| 7:30 | Registration (Foyer) | |
| Principal Investigators Introductory Meeting Session I Chair: Moses Joloba | ||
| 8:30-8:35 | Welcome & Introductions: Professor & Dean Moses Joloba | |
| 8:35-10:00 | Overview of H3Africa & Policy Highlights Presenters: Michelle Skelton, Nicola Mulder, Alia Benkahla, Paulina Tindana, Jantina de Vries, Alice Matimba | |
| 10:00-10:15 | Tea/Coffee Break Poster Sessions (Foyer & Balcony) (15 min) | |
| 10:15-11:15 | H3Africa Principal Investigators
Chairs: Clement Adebamowo & Nicola Mulder (Kalangala Hall) |
Data & Biospecimen Access Committee(DBAC) Chair Akin Abayomi (Boardroom2) |
| 11:15-12:00 | DBAC Joins the PI Meeting | |
| 12:00-13:00 | Lunch/Poster Sessions (Foyer & Balcony) | |
| Principal Investigators Session II Chair:Ruth Chadwick Ethics,Legal&SocietyIssues | ||
| 13:00-13:15 | Project: Ethical and social issues in informed consent processes in African genomic research PI: Erisa Sabakaki
Presenter: Erisa Sabakaki PI: Erisa Sabakaki Presentation: 13 min Q&A: 2min |
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| 13:15-13:30 | Project: Indigenous Linguistic and Cultural Conceptsof Heritability and Comprehensionof Genomics Research in Africa (INDIGENE) Study
Presenter:ClementAdebamowo PI:Clement Adebamowo Presentation:13 min Q&A:2min |
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| 13:30-13:45 | Project:Stigma in African genomics research on Schizophreni and Rheumatic Heart Disease
Title:Is stigma a risk in African genomics research? Findings from a project on schizophrenia and rheumatic heart disease Presenter:Jantina de VriesPI:Jantina de Vries Presentation:13min Q&A:2min |
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| 13:45-14:00 | Project/Title:Genomics Inheritance Legal and Social
Issues Presenter: Alice Matimba PI: Alice Matimba Presentation:13 minQ&A:2min |
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| 14:00-14:15 | Project/Title:Community Engagement fo rH3Africa Biobanking Research:The Tygerberg Model
Presenter:MelanyHendricksPI:KeymanthriMoodley Presentation:13 minQ&A:2min |
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| 14:15-14:30 | Project/Title: Individual Finding in Genetic Research in Africa(IFGeneRA) Presenter: Ambroise Wonkam PIs: Ambroise Wonka & Jantina de Vries Presentation: 13 min Q&A:2min | |
| 14:30-14:45 | Tea/Coffee Break Poster Sessions (Foyer & Balcony) (15 min) | |
Working Group Session I |
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| Kalangala Hall | Ngamba Room | Bulago Room | |
| 14:45-16:15 | Community Engagement | Joint Phenotype | GAWP Subgroup |
| Chair: Paulina Tindana | Chair: Neil Hanchard | ||
| Rapporteurs: Jennifer Troyer & Mark Guyer | Chair: Nicola Mulder | Rapporteur: Gabriel Batzli & Laura Skow | |
| Rapporteurs: Audrey | |||
| Duncanson & Jeff | |||
| Struewing | |||
| 16:15-17:45 | Ethics & Regulatory Issues | Cardiovascular Disease | |
| Chair: Aminu Yakubu | Chairs: Akinlolu Ojo & | ||
| Rapporteurs: Ebony Madden | Sally Adebamowo | ||
| & Katherine Littler | Rapporteurs: Ken Wiley | ||
| & Charles Rotimi | |||
| 17:45-19:00 | H3Africa Sustainability Working Group Meeting
Chairs: Raj Ramesar & Dwomoa Adu Rapporteurs: Jennifer Troyer & Jenniffer Maroa |
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| 19:00 | Drinks Reception at the Marina | ||
| 19:30 | Dinner Lakeside at the Marina | ||
Friday,23 March 2018 ,Serena LakeVictoria Kalangala Hall |
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| 8:00 | Registration | ||
| 8:30-8:35 | Introductions: Professor & Dean Moses Joloba | ||
| 8:35-8:40 | Welcome:Principal of the College of Health Science University of Makerere by Associate Professor Charles Ibingira | ||
| 8:40-9:00 | Opening: Minister of Science and Technology the Honourable Dr. Elioda Tumwesigye | ||
| Principal Investigators Session III Chair: Rex Chisholm Bioinformatics &Training | |||
| 9:00-9:15 | Project: West African Sustainable Leadership and Innovation Training in Bioinformatics Research (WASLITBRE)
Presenter: Ezekiel Adebiyi PI: Ezekiel Adebiyi, Peter Amoako-Yirenky, Seydou Doumbia Presentation: 13 min Q&A: 2min |
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| 9:15-9:30 | Project: West African Center of Excellence for Global Health Bioinformatics Research Training Presenter: Mamadou Wele PI: Seydou Doumbia, Jian Li, Jeffrey Shaffer Presentation: 13 min Q&A: 2min | ||
| 9:30-9:45 | Project: Nurturing Genomics and Bioinformatics Research Capacity in Africa (BRecA) Presenter:David Kateete PI:David Kateete,DaudiJ Jingo,Irving Jordan,Graeme Mardon Presentation:13 minQ&A:2min | ||
| 9:45-10:00 | Project:Eastern Africa Network for Bioinformatics Training Presenter: Daniel Masiga PI: Daniel Masiga Presentation:13min Q&A:2min | ||
| 10:00-10:25 | Project: H3ABioNet: a sustainable African Bioinformatics Network for H3Africa Title: H3ABioNet: informatics network for H3Africa Presenter: Nicola Mulder PI: NicolaMulder
Presentation: 23 min Q&A: 2min |
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| 10:25-10:40 | Title:Professional capacity building (and collaborative networking) to support local biomedical research using bioinformatics and related data-intensive sciences.
Presenter: Darrell Hurt, Chris Whalen and Mike Tartakovsky Presentation: 13 min Q&A: 2min |
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| 10:40-11:00 | Tea/Coffee Break Poster Sessions (Foyer & Balcony) (20 min) | ||
| Working Group Session II | |||
| Kalangala Hall | Ngamba Room | Boardroom 2 | |
| 11:00-12:00 | Education & Coordinated Training WG Chair: Samar Kassim
Rapporteurs: Laura Povlich & Maria Giovanni |
Chair: Mogomotsi Matshaba | Data & Biospecimen Access Committee Chair: Akin Abayomi |
| 12:00-13:00 | Lunch | ||
| Principal Investigators Session IV Chairs: Kay Davies & Cathrine Hoyo | |||
| 13:00-13:15 | Project: Eyes of Africa: The Genetics of Blindness
Presenter: Adeyinka Ashaye PI: Adeyinka Ashaye Presentation: 13min Q&A: 2min |
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| 13:15-13:30 | Project: Hearing Impairment Genetics Studies in Africa (HI-GENES Africa) Presenter: Ambroise Wonkam PI: Ambroise Wonkam Presentation: 13 min Q&A: 2min | ||
| 13:30-13:45 | Project: Deciphering Developmental Disorders in Africa (DDD-Africa) – Evaluating Clinical Exome Sequencing in an African Setting
Presenter:ZaneLombardPI:ZaneLombard Presentation:13 minQ&A:2min |
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| 13:45-14:00 | Project:TransgenerationalEpigenomicsofTrauma andPTSDin Rwanda PIs:LeonMutesa,MonicaUddin,Derek Wildman,StefanJansen | ||
| 14:00-14:15 | Project/Title:Transgenerational Effects of Maternal Stressors:Investigating the Role of Infant Gene Expression
Presenter:Nastassja Koen PIs:Dan Stein,Nastassja Koen,Kerry Ressler,Aliza Wingo Presentation:13 minQ&A:2min |
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| 14:15-14:30 | Tea/Coffee Break Poster Sessions (Foyer & Balcony) (15 min) | ||
| Principal Investigators Session V Chairs: Barry Bloom & Francine Ntoumi | |||
| 14:30-14:45 | Project: SickleGenAfrica:Sickle Cell Disease Genomics Network of Africa PIs: Dr. Solomon Ofori-Acquah, Dr. Gordon Awandare, Dr. Julie Makani Presentation: 13 min Q&A: 2min | ||
| 14:45-15:05 | Project:Trypanogen+:GeneticDeterminantsofTwoNeglectedTropicalDiseases Presenter:Enock MatovuPI:Enock Matovu
Presentation: 18 min Q&A: 2min |
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| 15:05-15:30 | Project: TB Genetics Network in Africa (TBGENAfrica) Presenter: Abraham Aseffa PI: Abraham Aseffa Presentation: 13 min Q&A: 2min | ||
| 15:30-15:45 | Project/Title: Genomic Characterization and Surveillance of Microbial Threats in West Africa Presenter: Christain Happi PI: Christain Happi
Presentation: 13 min Q&A: 2min |
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| 15:45-16:00 | Tea/Coffee Break Poster Sessions (Foyer & Balcony) (15 min) | ||
| Working Group Session III | |||
| Ngamba Room | Bulago Room | Kalangala Hall | |
| 16:00-17:00 | Study Coordinator Working Group
Rapporteurs: Robin Mason & Karen Lacourciere |
Genome Analysis WG Session Chairs: Adebowala Adeyemo & Zane Lombard (GPW Sub Group Update on the Publication Chair: Neil Hanchard | |
| 17:00-18:00 | H3Africa IEC Meeting
Venue: Boardroom 2 |
H3Africa Steering Committee Meeting (with Funders) | |
| 18:00-19:00 | H3AfricaSustainabilityWG,SC& IECjointsessionUpdate onCARI by ThomasKariuki
Rapporteurs: Barbara Sina & Concepcion Nierras |
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| 19:00 | Drinks Reception at Coliseum Garden | ||
| 19:30 | Formal Dinner at Coliseum Garden (After Dinner Speaker TBC/A) | ||
| Principal Investigators Session V Chair: Ayoade Oduola | ||
| 9:00-9:15 | Project:Pan-AfricaMalariaGeneticEpidemiology(PAMGEN) Presenter: Alfred Amambua Ngwa PI: Alfred AmambuaNgwa Presentation: 13 min Q&A:2min | |
| 9:15-9:30 | Project: Center for Research on the Respiratory Microbiota of African Children (ReMAC)
Title:ReMAC:understandingtheroleof theupperairwaymicrobiotainlung healthofAfrican children Presenter:MarkNicol PI:MarkNicol Presentation:13 minQ&A:2min |
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| 9:30-9:50 | Project: Stroke Investigative & Educational Network (SIREN) Title: Understanding stroke in Africa: Charting new paths Presenter: Mayowa Owolabi PI: Mayowa Owolabi Presentation: 18 min Q&A: 2min | |
| 9:50-10:05 | Project:AfricanFemale BreastCancerEpidemiology(AFBRECANE)Study Presenter:ClementAdebamowoPI:ClementAdebamowo | |
| 10:05-10:20 | Project: Breast Milk Microbiota Influence on Infant Immunity and Growth (BEAMING)
Title: BEAMINIG study: Influence of breast milk microbiota on HIV exposed uninfected infant immunity and growth Present: Alash’le Abimiku PI: Alash’le Abimiku Presentation: 13 min Q&A: 2min |
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| 10:20-10:35 | Project/Title:Immunoglobulingene diversityinan Africanpopulationand impactonantibody function in HIVinfection
Presenter: Cathrine Scheepers PI: Lynn Morris Presentation: 13 min Q&A: 2min |
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| 10:35-10:55 | Tea/Coffee Break (Foyer & Balcony) (20 min) | |
| Working Group Session IV | ||
| Kalangala Hall | Ngamba Room | |
| 10:55-12:30 |
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Environmental Health
Rapporteur: Bonnie Joubert |
| Working Group Session IV Chair: Rex Chisholm | ||
| 12:30-13:00 | H3Africa Biorepositories-Joint PI Presentation
Project: Integrated Biorepository of H3Africa Uganda – IBRH3U PI: Moses Joloba Project: Estalishment of an H3Africa Biorepository at Clinical Laboratory Services PI: Elizabeth Mayne Project: IHVN H3Africa Biorepository (I-HAB) Initiative PI: Alash’le Abimiku Presentation: 25min Q&A: 5min |
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| 13:00-14:00 | Lunch | |
| Working Group Report Back | Presenter (8 min each) | |
| Chairs: Ayoade Oduola & Rex Chisholm | ||
| 14:00-15:00 | Community Engagement | Paulina Tindana |
| Ethics & Reg Issues | TBA | |
| Study Coordinators | TBA | |
| Education & Coordinated Training | Samar Kassim | |
| Discussion | ||
| Chairs: Kay Davies & Barry Bloom | ||
| 15:00-16:00 | Mogomotsi Matshaba | |
| CVD | Akinlolu Ojo | |
| Biorepository | Elizabeth Mayne | |
| Alia Benkahla | ||
| Adebowale Adeyemo | ||
| 16:00-16:10 | Discussion & IEC Feedback | |
| 16:10-16:15 | H3Africa Steering Committee Chair Closes the Meeting | |
| 19:00 – 21:00 | H3Africa Fellows’ Dinner (Venue-TBA) | |
Sunday, 25 March 2018 Lake Victoria Serena |
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| 7:00 a.m. | Meet at Hotel Entrance, Bus departs for Kampala Makerere University |
| 9:00 a.m. | Bus Arrive Makerere: LOC hosts site vists Trypanogen/Biorepository |
| 11:00 & 12:00 p.m. | Bus departs to Entebbe Airport (TBC) & Hotel |