H3Africa Consortium Group Photo

 

Sheraton Addis Hotel
Addis Ababa, Ethiopia
October 8-10, 2012

Meeting Report

Agenda

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Monday, October 8

SESSION 1: Background to the H3Africa Initiative
Chair: Charles Rotimi, NIH-Center for Research on Genomics and Global Health

9:00 a.m.Overview of the H3Africa Initiative 
Charles Rotimi, NIH-Center for Research on Genomics and Global Health
9:15 a.m.H3Africa: The Funders perspective 
Pat Goodwin, Wellcome Trust
9:35 a.m.H3Africa: The Funders perspective  
Eric Green, NIH-National Human Genome Research Institute
9:55 a.m.Questions

SESSION 2: Wellcome Trust Research Network
Chair: Audrey Duncanson, Wellcome Trust

10:00 a.m.Burden, Spectrum and Aetiology of Type 2 Diabetes in Sub-Saharan Africa
Albert Amoah, University of Ghana Medical School
10:25 a.m.Genetics of Rheumatic Heart Disease & Molecular Epidemiology of Streptococcus Pyogenes Pharyngitis
Bongani Mayosi, University of Cape Town
10:50 a.m.TrypanoGEN: An Integrated Approach to the Identification of Genetic Determinants of Susceptibility to Trypanosomiasis
Enock Matovu, Makerere University of Veterinary Medicine
11:15 a.m.Coffee break

SESSION 3: NIH Collaborative Centres and Research Projects
Chair: Jane Peterson, NIH-National Human Genome Research Institute

11:45 a.m.Genomic and Environmental Risk Factors for Cardiometabolic Disease in Africans
Michele Ramsay, University of Witswatersrand & NHLS
12:10 p.m.H3Africa Kidney Disease Research Network Organization
Dwomoa Adu, University of Ghana Medical School
12:35 p.mContribution of genetic variation to pharmacokinetic variability and toxicity in patients undergoing multi-drug tuberculosis treatment in Sub-Saharan Africa: RAFAgene project
Dissou Affolabi, National Hospital for Tuberculosis and Pulmonary Diseases, Benin
1:00 p.m.Lunch

SESSION 4: NIH Bioinformatics and Biorepository Projects
Chair: Mark Guyer, NIH-National Human Genome Research Institute

2:00 p.m.Background to Bioinformatics Network
Jane Peterson, NIH-National Human Genome Research Institute
2:10 p.m. 

H3ABioNet: A sustainable African bioinformatics network for H3Africa
Nicola Mulder, Computational Biology Group, University of Cape Town

2:30 p.m.Discussions
3:00 p.m.Background to Biorepository Grants
Jane Peterson, NIH-National Human Genome Research Institute
3:10 p.m.IHVN H3Africa Biorepository (I-HAB) Initiative

Alash’le G. Abimiku, Institute of Human Virology, Nigeria

3:30 p.m.Development of H3 Africa Biorepositories to facilitate studies on Biodiversity, Disease and Pharmacogenomics of African Populations
Akin Abayomi, University of Stellenbosch
3:50 p.m.Discussion
4:15 p.mTea Break
4:30 p.m.Networking / Opportunity to find out more from commercial exhibitors

4:30 p.m.Press Briefing

7:00 p.mDrinks and Presentation:

Leverage of Partnerships on Science, Technology and Innovation in Africa
Diran Makinde, NEPAD Planning and Coordinating Agency
7:30 p.m.Dinner
8:30 p.m.After-dinner Talk: Enhanced Breeding of African Traditional Food Crops Utilizing NextGeneration Genomic Tools to Help End Chronic Hunger and Malnutrition
Howard-Yana Shapiro, Mars Incorporated
Tuesday, October 9
9:00 a.m.Continuation of Biorepository Discussion 
Alash’le G. Abimiku, Institute of Human Virology, Nigeria and Akin Abayomi, University of Stellenbosch

SESSION 5: Sharing Protocols and Data
Chairs: Rex Chisholm, Feinberg School of Medicine, Northwestern University
Carlos Bustamante, School of Medicine, Stanford University

9:15 a.m.Lessons from other Genomics Projects 
Mark Guyer, NIH-National Human Genome Research Institute
9:30 a.mSharing: the H3Africa Vision 
Charles Rotimi, NIH-National Human Genome Research Institute
9:50 a.m.Discussion
10:00 a.m.Sharing Protocols – Best Practices
Carlos Bustamante, School of Medicine, Stanford University
10:20 a.m.Discussion
10:30 a.m.Coffee Break
11:00 a.m.Sharing Data – Best Practices 
Rex Chisholm, Feinberg School of Medicine, Northwestern University
11:20 a.m.Discussion
11:30 a.m.Breakout Groups
12:15 p.m.Report Back
12:45 p.m.Lunch

SESSION 6: Consent and Feedback of Results
Chairs: Ruth Chadwick, Cesagen, Cardiff University
Charmaine Royal, Duke Institute for Genome Sciences and Policy

1:45 p.m.Consent: State of the Art and Issues Arising 
Ruth Chadwick, Cesagen, Cardiff University
2:05 p.m.Returning Research Results: The Why, What, Where, When, How and Who? 
Charmaine Royal, Duke Institute for Genome Sciences and Policy
2:30 p.m.Community Harms in Genomics Research in Africa 
Clement Adebamowo, Institute of Human Virology, Nigeria
2:50 p.m.Discussion
3:30 p.m.Tea Break
4:00 p.m.Breakout Groups
4:45 p.m.Report Back
5:30 p.m.Opportunities for Networking and Discussion with Funders

7:00 p.m.Drinks
7:30 p.m.Dinner
Wednesday, October 10
7:30 a.m.Private Breakfast for H3Africa Independent Expert Committee Members and Funders
9:00 a.m.Review of Day 2 and Introduction to Day 3
Pat Goodwin, Wellcome Trust

SESSION 7: Building Capacity Across the Network
Chairs: Solomon Nwaka, WHO-TDR
Ayoade Odoula, Institute for Infectious Diseases of Poverty (IIDP/IRMP), Nigeria

9:15 a.m.Introductory Comments

  • Sciences and Health in Africa: WHY Build Capacy for Genomics Research
    Solomon Nwaka, WHO-TDR
    Ayoade Odoula, Institute for Infectious Diseases of Poverty, IIDP/IRMP, Nigeria
    Philip Awadalla, University of Montreal
  • H3ABioNet: Buiilding Capacity in Bioinformatics 
    Nicola Mulder, Computational Biology Group, University of Cape Town
10:15 a.m.Discussion
11:00 a.m.Coffee
11:30 a.m.Breakout Groups
12:15 p.m.Report Back
1:00 p.m.Lunch

SESSION 8: The H3Africa Initiative – What will success look like?
Chairs: Pat Goodwin, Wellcome Trust and Eric Green, NIH-National Human Genome Research Institute

2:00 p.m.Introductory Comments – Members of H3Africa Independent Expert Committee
2:00 p.m.Discussion and Breakout Groups
3:30 p.m.Review of Meeting and Next Steps 
4:00 p.m.Close of Meeting