Third H3Africa Consortium Meeting

The Radisson Blue Gautrain Hotel

Sandton, South Africa

3-6 October 2013

Agenda

Thursday, October 03, 2013 Third H3Africa Consortium Meeting Day 1
07:00-08:30		Registration & Welcome Coffee/Tea	VENUES
08:30-10:00		PARALLEL SESSIONS Biorepository Users Working Group Chairs Akin Abayomi and Alan Christoffels Discussion Facilitators Michelle Skelton Genome Analysis Working Group Chairs Zane Lombard Discussion Facilitators Jeff Struewing Ethics &Regulatory Issues Working Group Chairs Jantina De Vries Discussion Facilitators Katherine Littler Education and Coordinated Training Working Group (08h30 – 09h30) Discussion Facilitators Lara Bethke Study and Coordinators Discussion Group (09h30 – 10h00) Discussion Facilitators Lara Bethke	Main Station One Main Station Two Main Station Three Union Station Union Station
10:00-10:30		Tea/Coffee break	Outside Meeting area
10:30-12:30		PARALLEL SESSIONS Biorepository Principle Investigators Chairs Sue Penno Discussion Facilitators Alash’le Abimiku Genome Analysis Working Group Chairs Debo Adeyemo and Zane Lombard Discussion Facilitators Jeff Struewing Ethics &Regulatory Issues Working Group Chairs Jantina De Vries Discussion Facilitators Katherine Littler H3ABionet Infrastructure and User Support Working Group	Main Station One Main Station Two Main Station Three Union Station
12:30-14:00		Lunch	Gautrain Room
14:00-15:00		PARALLEL SESSIONS Data Sharing, Access, Release Working Group Chairs Nicola Mulder and Bamidele Tayo Discussion Facilitators Audrey Duncanson Phenotype Harmonization Working Group Chairs Alia Benkahla Discussion Facilitators Publications & Marker Paper Working Group Chairs Michele Ramsay and Enock Matovu Discussion Facilitators Mark Guyer and Audrey Duncanson Communications & Outreach Working Group Chairs Akin Abayomi Discussion facilitators Lara Bethke	Main Station One Main Station Two Main Station Three Union Station
15:00-15:30		Tea/Coffee break
15:30-16:30		PARALLEL SESSIONS Data Sharing, Access, Release Working Group Chairs Nicola Mulder and Bamidele Tayo Discussion Facilitators Maria Giovanni and Audrey Duncanson Phenotype Harmonization Working Group Chairs Alia Benkahla Discussion Facilitators Jeff Struewing Publications & Maeker Paper Working Group Chairs Michele Ramsay, Charles Rotimi, Enock Matovu Discussion Facilitators Mark Guyer and Audrey Duncanson Communications & Outreach Working Group Chairs Akin Abayomi Discussion Facilitators Jane Peterson & Lara Bethke	Main Station One Main Station Two Main Station Three Union Station
16:30-17:30		Steering Committee Meeting	Main Station One
17:30-18:00		Discussions Principle Investigators and Independent Expert Committee Principle Investigators and Project teams Principle Investigators and Funders	Main Station Two
18:00-19:00		Social hour	Pool deck
19:00		Dinner
Friday, October 04, 2013 Third H3Africa Consortium Meeting Day 2 (All meetings take place in the Gautrain room unless stated otherwise)
07:30-08:30		Welcome Coffee/Tea
08:30-08:35		Opening Remarks– Audrey Duncanson
08:35-09:30		Biorepository Working Group Chairs Charmaine Royal Discussion Facilitators Akin Abayomi, Alash’le Abimiku
09:30-10:30		Data Sharing, Access and Release Working Group Chairs Val Sheffield Discussion Facilitators Nicola Mulder, Bamidele Tayo
10:30-11:00		Tea/Coffee break
11:30-13:00		Ethics and Regulatory issues Working Group Chairs Ruth Chadwick Discussion Facilitators Jantina De Vries
13:00-14:00		Lunch
14:00-15:00		Genome Analysis Working Group Chairs Carlos Bustamante Discussion Facilitators Zane Lombard
15:00-16:00		Phenotype Harmonization Working Group Chairs George Mensah Discussion Facilitators Alia Benkahla
16:00-16:30		Tea/Coffee break
16:30-17:30		Publications & Marker Paper Working Groups Chairs Phillip Awadalla Discussion Facilitators Michele Ramsay, Enock Matovu
17:30-18:30		17:30 – 17:50: Education & Coordinated Training Working Group 17:50 – 18:10: Communications & Outreach Working Group 18:10 – 18:30: Study Coordinators Discussion Group Facilitator: Lara Bethke
18:30-19:30		Discussions Principle Investigators and Independent Expert Committee Principle Investigators and Project teams Principle Investigators and Funders
18:30-19:30		Social Hour – Pool Area, Radisson Hotel
19:30		Dinner
Saturday, October 05, 2013 Third H3Africa Consortium Meeting Day 3 (All meetings take place in the Gautrain room unless stated otherwise).
07:30-08:00	Welcome Coffee/Tea
08:00-08:30	Welcome & H3Africa Overview Kay Davies
SESSION 1
Bioinformatics – Chair: Kay Davies
08:30-08:50	H3ABioNet: A Sustainable African Bioinformatics Network for H3Africa Principle Investigator : Nicola Mulder
SESSION 2
Non-infectious Diseases – Chair: Val Sheffield
08:50-09:10	H3Africa Kidney Disease Research Network Principle Investigator : Dwomoa Adu
09:10-09:30	Genomic and Environmental Risk Factors for Cardiometabolic Disease in Africans Principle Investigator : Michele Ramsay / Osman Sankoh
09:30-09:50	Burden, spectrum and etiology of type 2 diabetes in sub-Saharan Africa Principle Investigator :Albert Amoah
09:50-10:10	The RHDGen Network: Genetics of rheumatic heart disease and molecular epidemiology of Streptococcus pyogenes pharyngitis Principle Investigator : Bongani Mayosi
10:10-10:30	Stroke Investigative Research & Educational Network (SIREN) Principle Investigator : Mayowa Ojo Owolabi
10:30-11:00	Tea/Coffee break
11:00-11:20	Clinical and genetic studies of hereditary neurological disorders in Mali Principle Investigator : Guida Landoure
11:20-11:40	Genomics of Schizophrenia in the South African Xhosa Co-Principle Investigator : Raj Ramesar
SESSION 3
Microbiome – Chair: Carlos Bustamante
11:40-12:00	African Collaborative Center for Microbiome and Genomics Research (ACCME) Principle Investigator : Clement Adebamowo
12:00-12:20	The nasopharyngeal microbiome and respiratory disease in African children Principle Investigator : Mark Nicol Patrick
12:20-13:30	Lunch
SESSION 4
Biorepository – Chair: Ruth Chadwick
13:30-13:50	IHVN H3 African Biorespository (I-HAB) Initiative Principle Investigator : Alash’le Abimiku
13:50-14:10	Development of H3 Africa Biorepositories to facilitate studies on Biodiversity, Disease & Pharmacogenomics of African Populations Principle Investigator : Akin Abayomi
14:10-14:30	Integrated Biorepository of H3Africa Uganda – IBRH3AU Principle Investigator : Moses Joloba
14:30-14:50	Establishment of an H3Africa Biorepository at Contract Laboratory Services Principle Investigator : Ute Jentsch
SESSION 5
Ethics – Chair: Charmaine Royal
14:50-15:10	Exploring Perspectives on Genomics and Sickle Cell Public Health Intervention Principle Investigator : Ambroise Wonkam
15:10-15:40	Tea/Coffee break
SESSION 6
Infectious Diseases – Chair: Philip Awadalla
15:40-16:00	Host and Microbial Genetic Determinants of Febrile Illness in West Africa Principle Investigator : Christian Happi
16:00-16:20	TrypanoGEN: An integrated approach to the identification of genetic determinants of susceptibility to trypanosomiasis Principle Investigator : Enock Matovu
16:20-16:40	Reprogramming of the Trypanosoma brucei epigenome during human infection: opportunities for new therapies Principle Investigator : Hugh-George Patterton
16:40-17:00	Collaborative African Genomics Network (CAFGEN) Principle Investigator : Gabriel Anabwani
17:00-17:20	RAFAgene: Contribution of genetic variation to pharmacokinetic variability and toxicity in patients undergoing multi-drug tuberculosis treatment in Sub-Saharan Africa Principle Investigator : Dissou Affolabi
17:20-17:40	Systems Biology for Molecular Analysis of Tuberculosis in Ethiopia Principle Investigator : Gobena Ameni
18:00-19:00	Steering Committee Meeting
Sunday, October 06, 2013 Genome Analysis Session The Maslow Hotel
8:30 – 8:35	Introduction Zané Lombard
8:35 – 8:45	Overview of H3Africa Audrey Duncanson
8:45 – 9:25	Population genomic variation across Africa Sub-Saharan genetic diversity and San and Khoe Himla Soodyall & Mattias Jakobsson
9:25 – 10:00	Current arrays for capturing variation in African populations & whole genome sequencing based approaches Manj Sandhu (AGVP)
10:00 –10:25	Imputation, meta-analysis & population stratification Dominic Kwiatkowski (MalariaGEN)
10:25– 10.50	Admixture and African populations Carlos Bustamante
10:50 – 1:40	Technologies and platforms for genomics in Africa Chair: Michele Ramsay Jian Tu BGI Paul Mola Life Technolgies Donovan Burger Separation Scientific SA Reinhard Hiller CPGR
11:40 –12:10	Panel Discussion Manj Sandhu Dominic Kwiatkowski Mattias Jakobsson Himla Soodyall Chairs: Carlos Bustamante and Michele Ramsay
12:10 –12:15	Closing remarks

Meeting Report

Report-Third-H3Africa-3-6-Oct-2013_finalAQN

The third H3Africa Consortium Meeting will be held on October 3-6, 2013 in Johannesburg, South Africa. The aims of the H3Africa Consortium meeting are to provide an opportunity for H3A investigators to update on the achievements on their projects, and for the working groups to have a face to face meeting and develop policies, materials and recommendations to standardize activities across the consortium. The meeting will also provide networking opportunities for awardees, the working groups, and funders, and to enable discussions on how to build research capacity across the Initiative and access new opportunities.
The outline of the meeting is as follows (see program):

3rd October H3Africa working group meetings (Radisson Blu hotel)
4th October H3Africa Consortium meeting (Radisson Blu hotel)
5th October H3Africa Project presentations *Open session (Radisson Blu hotel)
6th October African Genome variation session *Open session, ½ day (Maslow Hotel)

The meeting precedes the 15th Biennial Congress of the Southern African Society for Human Genetics (SASHG), which runs from the 6th to 9th October 2013 at the Maslow Hotel, see: http://www.sashg2013.co.za (website is currently down) for details.

The first 2 days of the H3Africa Consortium meeting are closed for Consortium members, but the last 2 are open to others who want to attend. Please register to attend (see registration information below).

Meeting venue

The main H3Africa Consortium Meeting from the 3-5th October will take place at the Radisson Blu hotel in Sandton, next to the Gautrain station: http://www.radissonblu.com/hotelsandton-johannesburg.
The Genome Variation session on the 6th October will take place at the Maslow hotel, which is 7-10 minute’s walk away.

Registration for all sessions are now closed

All attendees are required to register. For H3Africa consortium members, please register at: http://surveys.h3abionet.org/h3ajhb

Note:
Each project has a limit on the number of participants, additional people over and above these limits will be required to pay a registration fee of $250. Please check with your project PI which category you fall in.
Participants are responsible for their own travel arrangements and hotel bookings

For non-H3Africa consortium members, please register for the open sessions at:
http://surveys.h3abionet.org/h3ajhb-open